Results 41 to 50 of about 2,149,929 (236)

Prediction of material damage in orthotropic metals for virtual structural testing [PDF]

open access: yes, 2010
Models based on the Continuum Damage Mechanics principle are increasingly used for predicting the initiation and growth of damage in materials. The growing reliance on 3-D finite element (FE) virtual structural testing demands implementation and ...
Ravindran, S.
core   +6 more sources

A Nonlinear Creep-damage Constitutive Model of Mudstone Based on the Fractional Calculus Theory [PDF]

open access: yesJournal of Petroleum Science and Technology, 2017
During the flood development in an oil field, the creep characteristic of mudstone is one of the important factors causing casing damage. In this study, based on the theory of fractional order differential and taking into account the creep damage ...
Zhang Jun, Zeng Jia
doaj   +1 more source

Experimental and Numerical Investigation of Ballistic Resistance of Polyurea-Coated Aluminum Plates under Projectile Impacts

open access: yesCrystals, 2023
The effects of the spraying thickness and the position on the response of aluminum plates under impact loading were studied. The impact tests and numerical simulation were conducted for the penetration process of polyurea-coated 2024 aluminum plates with
Chenglong He   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

3D Numerical Solution for Natural Fracture Distribution in Tight-Sand Reservoirs Based on Damage Mechanics with Sets of 2D Seismic Data

open access: yesApplied Sciences
Natural fracture development in tight-sand gas reservoirs is strongly controlled by tectonic evolution yet remains difficult to characterize using conventional seismic interpretation due to limited resolution. This study presents a damage-mechanics-based
Meng Wang, Xinpu Shen, Qiyu Gao
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Damage Mechanics Experimental Background

open access: yesEngineering Transactions, 1988
The present paper is a synthetic review of available experimental results, concerning damage nucleation and growth in various materials at diverse loading conditions. An emphasis is placed on the physical complexity of the damage processes. To this end,
M. Basista
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The development of finite element software for creep deformation and damage analysis of weldment [PDF]

open access: yes
This paper presents the development of finite element software for creep deformation and damage analysis of weldment. The development and benchmark test of the software under plane stress, plane strain, axisymmetric, and 3 dimensional cases were reported
Xu, Qiang   +3 more
core   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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