Results 51 to 60 of about 79,411 (313)

Characterization of isotropic damage using double scalar variables [PDF]

, 2002
In this study, double scalar damage variables have been used to characterize the state of isotropic damage. The damage influence tensorrelating to the double scalar damage variables of damaged material isthus formulated based on the hypothesis of stress ...
Tang, CY, Peng, LH, Lee, TC, Shen, W
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

3D Numerical Solution for Natural Fracture Distribution in Tight-Sand Reservoirs Based on Damage Mechanics with Sets of 2D Seismic Data

Applied Sciences
Natural fracture development in tight-sand gas reservoirs is strongly controlled by tectonic evolution yet remains difficult to characterize using conventional seismic interpretation due to limited resolution. This study presents a damage-mechanics-based
Meng Wang, Xinpu Shen, Qiyu Gao
doaj   +1 more source

Principal component analysis and perturbation theory–based robust damage detection of multifunctional aircraft structure [PDF]

, 2013
A fundamental problem in structural damage detection is to define an efficient feature to calculate a damage index. Furthermore, due to perturbations from various sources, we also need to define a rigorous threshold whose overtaking indicates the ...
HAJRYA, Rafik, MECHBAL, Nazih
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Damage Mechanics Experimental Background

Engineering Transactions, 1988
The present paper is a synthetic review of available experimental results, concerning damage nucleation and growth in various materials at diverse loading conditions. An emphasis is placed on the physical complexity of the damage processes. To this end,
M. Basista
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evolution of Localized Damage Zone in Heterogeneous Media [PDF]

, 2010
Evolution of localized damage zone is a key to catastrophic rupture in heterogeneous materials. In the present article, the evolutions of strain fields of rock specimens are investigated experimentally.
白以龙, Hao SW, 柯孚久, 夏蒙棼, Bai YL   +4 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Combination of fracture and damage mechanics for numerical failure analysis [PDF]

, 1999
A new approach for the analysis of crack propagation in brittle materials is proposed, which is based on a combination of fracture mechanics and continuum damage mechanics within the context of the finite element method.
Vroonhoven, JCW Jos van, Borst, de, R., Borst, R René de, J.C.W.van Vroonhoven, Vroonhoven, van, J.C.W., R.de Borst   +5 more
core   +1 more source