Results 101 to 110 of about 2,619,273 (303)

Initial stages of cavitation damage and erosion on copper and brass tested in a rotating disk device [PDF]

open access: yes
In view of the differences in flow and experimental conditions, there has been a continuing debate as to whether or not the ultrasonic method of producing cavitation damage is similar to the damage occurring in cavitating flow systems, namely, venturi ...
Rao, B. C. S., Rao, N. S. L., Rao, P. V.
core   +1 more source

Nanoscale damage during fracture in silica glass [PDF]

open access: yes, 2006
We report here atomic force microscopy experiments designed to uncover the nature of failure mechanisms occuring within the process zone at the tip of a crack propagating into a silica glass specimen under stress corrosion.
Bonamy, Daniel   +7 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

A Comparative Study on the Flexural Behavior of UHPC Beams Reinforced with NPR and Conventional Steel Rebars

open access: yesBuildings
This study investigates how different longitudinal steel rebars influence the flexural performance and cracking mechanisms of reinforced ultra-high-performance concrete (UHPC) beams, combining axial tensile tests using acoustic emission monitoring with ...
Jin-Ben Gu   +4 more
doaj   +1 more source

Mechanism of DNA damage tolerance

open access: yesWorld Journal of Biological Chemistry, 2015
DNA damage may compromise genome integrity and lead to cell death. Cells have evolved a variety of processes to respond to DNA damage including damage repair and tolerance mechanisms, as well as damage checkpoints. The DNA damage tolerance (DDT) pathway promotes the bypass of single-stranded DNA lesions encountered by DNA polymerases during DNA ...
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

In-plane shear constitutive model for 2D-C/SiC composites

open access: yesJournal of Aeronautical Materials
In order to characterize in-plane shear behavior of 2D-C/SiC composites,a macroscopic cross-ply laminate model and a microscopic mini-composite model were proposed,considering damage mechanisms such as matrix cracking,interface debonding,and fiber ...
LIN Jiangrong, YANG Chengpeng, JIA Fei
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Experimental and Numerical Study on the Blast Performance of RC Shear Walls Under Uniaxial Compression

open access: yesBuildings
This study addresses a critical gap in blast-resistant design by investigating the influence of axial compression ratio—a previously underexplored parameter—on the dynamic response of reinforced concrete (RC) shear walls under close-in explosions.
Wenzhe Luo   +3 more
doaj   +1 more source

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