Results 111 to 120 of about 2,619,273 (303)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
eXPRESS Polymer Letters, 2008 The influence of α-and β-nucleating agents on the fracture performance of two different 32 wt% rubber modified isotactic Polypropylene (iPP) reactor blends is discussed as a function of the phase morphology of the investigated systems ...
doaj +1 more source
Allocating environmental costs among heterogeneous sources: The linear damage equivalent mechanism. [PDF]
A group of firms has to divide the costs associated with environmental damages jointly generated as a by-product of their heterogeneous production activities.
Arguedas, Carmen, Kranich, Laurence
core
, 2004 Molecular dynamics simulations have been used to study a collective atomic transport phenomenon by repeated Ar$^+$ irradiations in the Ti/Pt interfacial system. The ion-induced injection of surface atoms to the bulk, the ejection of bulk atoms to the top
Averback +25 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Time Course of PR of UV-Induced Chromosomal Aberrations and Lethal Damage in G1 Xenopus Cells [PDF]
, 1977 Synchronous cultures of early G1 cells were exposed to UV and their ability to photoreactivate lethal and aberrational damage was determined as a function of time following UV exposure.
Griggs, H. Gaston, Payne, Jan
core +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Mechanical Chondrocyte Damage Thresholds
ASME 2012 Summer Bioengineering Conference, Parts A and B, 2012 Chondrocyte content in articular cartilage is very low. Only 2% to 5% of the tissue volume consists of chondrocytes [1]. Yet, these cells are responsible for maintenance of the tissue. Hence, the loss of chondrocytes that is often occurring at an early stage of cartilage degeneration is detrimental to articular cartilage.
Turnhout, van, M.C. +3 more
openaire +3 more sources