Results 111 to 120 of about 1,333,549 (315)
Shock-Induced Damage in Rocks: Application to Impact Cratering [PDF]
, 2006 Shock-induced damage beneath impact craters is studied in this work. Two representative terrestrial rocks, San Marcos granite and Bedford limestone, are chosen as test target.
Ai, Huirong (Anita)
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Chemical damage of screw pump stator material in crude oil environment
Hecheng xiangjiao gongyeScrew pump stator material was prepared with hydrogenated nitrile rubber as raw material, and the chemical aging damage of the screw pump stator material in different crude oil environment temperatures was studied by simulating real oil production ...
LI Hong-tai, WANG Chao, ZHANG Zi-cheng, TAN Jin-zhu
doaj +1 more source
Mechanical Chondrocyte Damage Thresholds
ASME 2012 Summer Bioengineering Conference, Parts A and B, 2012 Chondrocyte content in articular cartilage is very low. Only 2% to 5% of the tissue volume consists of chondrocytes [1]. Yet, these cells are responsible for maintenance of the tissue. Hence, the loss of chondrocytes that is often occurring at an early stage of cartilage degeneration is detrimental to articular cartilage.
Turnhout, van, M.C. +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Development of Advanced Creep Damage Constitutive Equations for Low CR Alloy Under Long-Term Service
Low Cr alloys are mostly utilized in structural components such as steam pipes, turbine generators and reactor pumps operating at high temperatures from 400℃ to 700℃ in nuclear power plants.
Xu, Qihua
core
AUTEX Research Journal, 2018 The quasi-static tensile damage behavior of one type of layer-to-layer 3-Dimensional Angle-interlock Woven Composite (3DAWC) was tested and analyzed in this paper. Incorporated with the acoustic emission (AE) events monitoring, the mechanical behavior of
Ma Qian +6 more
doaj +1 more source