Results 61 to 70 of about 4,459,810 (225)
Study on flexural properties of coal gangue powder asphalt mixture under freeze-thaw cycles
Materials Research Express, 2022 In order to study the influence of freeze-thaw cycle on the flexural performance of asphalt pavement, semi-circular flexural test (SCB) is carried out.
Jinrong Wu +3 more
doaj +1 more source
MECHANISM OF ALCOHOLIC TESTICULAR DAMAGE
The Japanese Journal of Urology, 1992 To observe the mechanism of alcoholic testicular damage, in a previous experiment we used weanling male SD rats aged 45 days, weighing about 200 g, and fed a liquid diet (Lieber's) containing 5% ethanol. The latter accounted for 36% of total caloric intake for 7 weeks, but did not result in testicular atrophy.
Shirai, Takashi, Ikemoto, Isao
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Applied Sciences, 2018 Understanding the tensile failure mechanisms in carbon fiber woven composites based on the acoustic emission (AE) technique is a challenging task.
Wei Zhou, Peng-fei Zhang, Yan-nan Zhang
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Development and Validation of a Wheel Wear and Rolling Contact Fatigue Damage Model [PDF]
, 2013 This paper summaries the development of a damage model to predict the deterioration rates of the wheel tread in terms of wear and rolling contact fatigue (RCF) damage.
Bevan, Adam +5 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Geomatics, Natural Hazards & RiskIn underground mining, common issues include surface subsidence and tailings accumulation. To address these issues, the layered tailings cemented filling technique is frequently utilized.
Pengyu Wang +4 more
doaj +1 more source
Effect of hygrothermal environment on mechanical properties and damage mechanism of CFRP
Cailiao gongcheng, 2019 The moisture absorption properties of carbon fiber reinforced plastics (CFRP) laminates treated with three kinds of hygrothermal environments (relative humidity 85% RH, temperature 25, 70, 85℃ respectively) were investigated by accelerated moisture ...
YANG Xu-dong +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source