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Mechanisms of tissue damage in arthritis

Seminars in Immunopathology, 2014
The destruction of articular structures in the course of inflammatory arthritides such as rheumatoid arthritis (RA) or seronegative spondyloarthropathies is the most serious direct consequence of these diseases. Indeed, joint damage constitutes the "organ damage" of RA and-just like in all other diseases with organ involvement-such damage will usually ...
Stephan, Blüml   +2 more
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Mechanisms of ischemic brain damage

Current Cardiology Reports, 2003
Neurologic complications from cerebral ischemia occur frequently following cardiac arrest, as well as in the perioperative period in cardiac surgery. The cellular and molecular mechanisms of cerebral ischemia are complex. This article discusses several important cell death and salvage pathways that are important in experimental cerebral ischemia that ...
Anish, Bhardwaj   +3 more
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Liver damage: mechanisms and management

British Medical Bulletin, 1994
Despite recent advances in our knowledge of the mechanisms of alcohol-induced liver damage, abstinence from alcohol and supportive measures remain the mainstays of management for the majority of patients. Progress has been made in our understanding of ethanol metabolism, the role of acetaldehyde, and both genetic and environmental factors responsible ...
D I, Sherman, R, Williams
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Damage mechanics with fabric tensors

Mechanics of Advanced Materials and Structures, 2006
A new formulation is presented to link continuum damage mechanics with the concept of fabric tensors within the framework of classical elasticity theory. A fourth-rank damage tensor is used and its exact relationship to the fabric tensors is illustrated. A model of damage mechanics for directional data is formulated using fabric tensors.
George Z. Voyiadjis, Peter I. Kattan
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The Mechanism and Damage of Snail Trails

2018 IEEE 7th World Conference on Photovoltaic Energy Conversion (WCPEC) (A Joint Conference of 45th IEEE PVSC, 28th PVSEC & 34th EU PVSEC), 2017
We found Sulfur in EVA film which has snail trails by Atomic Absorption spectrometer, Sulfur reacted with “Ag” in silver paste. Because the EVA film can’t reach the requirements of PV yellowing test, people have to add high temperature anti-yellowing agent, such as mercaptan, sulfide, thioester.
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Experimental Glaucoma Damage Mechanism

Archives of Ophthalmology, 1983
To the Editor. —In the JanuaryArchives(1983;101:94-97) Sossi and Anderson reported the results of an experiment on the mechanism of damage to cat optic nerve by intraocular pressure elevation of four hours, using the degree of axonal transport block as a measure of axonal injury. In some animals, BP was artificially lowered or raised to produce a wide
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The mechanism of liposomal damage by taurocholate

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1987
The stability of small unilamellar vesicles formed by egg-yolk phosphatidylcholine (PC) has been examined in the presence of sodium taurocholate. The permeability of the vesicular membrane changes as the total taurocholate concentration increases, until a transformation from mixed bile salt/PC vesicles to mixed micelles occurs.
P, Walde, J, Sunamoto, C J, O'Connor
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Mechanism of cardiac damage in anoxia

American Journal of Physiology-Legacy Content, 1959
The following hypothesis is suggested to explain the mechanism of anoxic damage in cardiac tissue. Lactic acid accumulation, resulting from anoxia, overcomes the buffer capacity of the sarcoplasm. The consequent increased intracellular acidity leads to activation of proteolytic enzymes in the heart tissue and thus to destruction of apoenzyme protein ...
R L, DEHAAN, J, FIELD
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Phototoxicity to the Retina: Mechanisms of Damage

International Journal of Toxicology, 2002
Light damage to the retina occurs through three general mechanisms involving thermal, mechanical, or photochemical effects. The particular mechanism activated depends on the wavelength and exposure duration of the injuring light. The transitions between the various light damage mechanism may overlap to some extent.
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On mechanical mechanism of damage evolution in articular cartilage

Materials Science and Engineering: C, 2017
Superficial lesions of cartilage are the direct indication of osteoarthritis. To investigate the mechanical mechanism of cartilage with micro-defect under external loading, a new plain strain numerical model with micro-defect was proposed and damage evolution progression in cartilage over time has been simulated, the parameter were studied including ...
Yu-Tao, Men   +4 more
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