Results 101 to 110 of about 43,457,732 (328)
Competition between mesoplasticity and damage under HCF – Elasticity/damage shakedown concept [PDF]
, 2007 Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112306003240The aim of this paper is to present new modelling dedicated to multiaxial high cycle fatigue (HCF), and applied to polycrystalline metals.
DRAGON, André +2 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
矿业科学学报, 2019 Dynamic caustic experimental method and numerical simulation method were used to study the crack propagation rules and the tension/compression damage zone at the end of boreholes in the planar model.The results show that the effect of different length ...
Li Qing +5 more
doaj +1 more source
Modelling of dynamic damage and failure in aluminium alloys [PDF]
, 2012 A physically based damage and failure model, applicable to orthotropic metals is proposed in this paper. To account for the physical mechanisms of failure, the concept of thermally activated damage initially proposed by Klepaczko [1], has been adopted as
Djordjevic, Nenad +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Principal component analysis and perturbation theory–based robust damage detection of multifunctional aircraft structure [PDF]
, 2013 A fundamental problem in structural damage detection is to define an efficient feature to calculate a damage index. Furthermore, due to perturbations from various sources, we also need to define a rigorous threshold whose overtaking indicates the ...
HAJRYA, Rafik, MECHBAL, Nazih
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Isotropic brittle damage and unilateral effect [PDF]
, 2010 This Note investigates the isotropic version of a general macroscopic model for brittle damage accounting for unilateral effects proposed by Welemane and Cormery (H. Welemane, F.
Hélène Welemane +3 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source