Results 71 to 80 of about 3,676,094 (356)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

USING GRAPHIC MODELING TO DETERMINE THE ANGLE BETWEEN THE ROLL AXES OFVEHICLES AT THE MOMENT OF COLLISION

open access: yesТеория и практика судебной экспертизы, 2015
An algorithm is proposed for determining the angle of relative position of vehicles at the moment of collision, using a graphic modeling method that involves building a damage model.
S. Zharkikh
doaj  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Modeling and experimental investigations of the stress-softening behavior of soft collagenous tissues [PDF]

open access: yes, 2013
This paper deals with the formulation of a micro-mechanically based dam-age model for soft collagenous tissues. The model is motivated by (i) a sliding filament model proposed in the literature [1] and (ii) by experimental observations from electron ...
Balzani, Daniel   +3 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Advanced ANN Prediction of Moisture Damage in CNT Modified Asphalt Binder [PDF]

open access: yesJournal of Soft Computing in Civil Engineering, 2017
Moisture penetration causes many direct and indirect distresses in flexible asphalt pavement. Due to damage in asphalt concrete and binder by moisture are the prime concern of failure for flexible pavement worldwide.
Md Arifuzzaman
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Damage mechanical properties of sandstone under combined action of freeze-thaw and load

open access: yesMeitan kexue jishu
Engineering rock mass in cold regions is subjected to the combined action of freeze-thaw and load for a long time, which causes deterioration in the mechanical properties of the rock mass.
Yongjun SONG, Jinghui CAO
doaj   +1 more source

Study on the influence of length-diameter ratio on the mechanical characteristics of cracks at the end of linear charges

open access: yes矿业科学学报, 2019
Dynamic caustic experimental method and numerical simulation method were used to study the crack propagation rules and the tension/compression damage zone at the end of boreholes in the planar model.The results show that the effect of different length ...
Li Qing   +5 more
doaj   +1 more source

Improving flood damage modelling

open access: yes, 2012
Scientific Technical Report; 12/13; ISSN 1610 ...
openaire   +3 more sources

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