Results 121 to 130 of about 619,613 (312)
Bovine colostrum is a health food supplement which prevents NSAID induced gut damage [PDF]
, 1999 BACKGROUNDNon-steroidal anti-inflammatory drugs (NSAIDs) are effective for arthritis but cause gastrointestinal injury. Bovine colostrum is a rich source of growth factors and is marketed as a health food supplement.AIMSTo examine whether spray dried ...
R A Goodlad +15 more
core +1 more source
Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections
mBio, 2016 Viruses of the Enterovirus genus of picornaviruses, including poliovirus, coxsackievirus B3 (CVB3), and human rhinovirus, commandeer the functions of host cell proteins to aid in the replication of their small viral genomic RNAs during infection.
Sonia Maciejewski +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Stability analysis of aircraft’s sudden damage process with ROA overlapping [PDF]
, 2018 Purpose The paper aims to propose a stability analysis method based on region-of-attraction (ROA) overlapping to evaluate the flight stability of the possible sudden damage process and guarantee flight safety in extreme cases.
Cunbao Ma, Jie Chen, Dong Song
core +1 more source
Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
Nature Communications, 2018 The mechanism through which Drosha and Dicer affect DNA repair is not clear. Here the authors use a high-throughput approach to uncover the role of Drosha in promoting DNA:RNA hybrids at DNA damaged sites.
Wei-Ting Lu +9 more
doaj +1 more source
Repair of DNA Double-Strand Breaks in Heterochromatin
Biomolecules, 2016 DNA double-strand breaks (DSBs) are among the most damaging lesions in DNA, since, if not identified and repaired, they can lead to insertions, deletions or chromosomal rearrangements.
Felicity Z. Watts
doaj +1 more source
Investigation of Stability Alarming for Retaining Wall Structures with Damage [PDF]
, 2017 To warn of the stability of retaining wall structures with damage, a simplified mechanical model and a finite element model of this retaining wall-soil coupling system are established. Via finite element model updating, a baseline finite element model of
Qian Xu
core +1 more source
Conception and Evolution of the Probabilistic Method for Damage Stability Assessment [PDF]
, 2021 The paper provides a full description and explanation of the probabilistic concept of ship damage stability from its conception to date, explaining its assumptions and limitations and describing its evolution for specific application to passenger ships ...
Romain Michalec +5 more
core
Designing for damage stability beyond design level [PDF]
, 2016 This paper describes the background and provides the rationale and the framework to embrace all feasible measures (passive/design and active/operational – normal and emergencies) for improving the damage survivability of RoRo Passenger ships.
Boulougouris, Evangelos +3 more
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source