Results 121 to 130 of about 6,560,570 (376)

Understanding Bullying and the Necessity for Prevention and Intervention in Schools [PDF]

open access: yes, 2019
The emotional stability and mental health of a student plays an essential role in his or her academic success. The emotional state of a student can be greatly damaged when he or she is the victim or perpetrator of bullying.
Thompson, Erica Marie
core   +1 more source

Active Fault Tolerant Control for Vertical Tail Damaged Aircraft with Dissimilar Redundant Actuation System

open access: yes, 2016
This paper proposes an active fault-tolerant control strategy for an aircraft with dissimilar redundant actuation system (DRAS) that has suffered from vertical tail damage.
Jun Wang   +4 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Dynamic Analysis of Variable-Stiffness Laminated Composite Plates with an Arbitrary Damaged Area in Supersonic Airflow

open access: yesAerospace
In response to the urgent need for performance predictions of damaged aerospace structures, this study undertakes a comprehensive investigation into the flutter characteristics of damaged variable-stiffness composite laminate (VSCL) plates. The governing
Pingan Zou   +3 more
doaj   +1 more source

Nonlinear Dynamic Stability of Cylindrical Reticulated Shells with Initial Damage [PDF]

open access: gold, 2023
Lei Li   +6 more
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]

open access: yes, 2007
The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM   +5 more
core  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth

open access: yesNature Communications, 2017
BRCA2 is essential for the repair of DNA damage; therefore, defects in BRCA2 are associated with tumorigenesis but also with increased susceptibility to genotoxic stress.
Jinping Liu   +6 more
doaj   +1 more source

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