Results 121 to 130 of about 172,653 (302)

An ex vivo comparison of the tensile strengthening properties of protein derivatives on damaged hair [PDF]

open access: yes, 2015
Conventional conditioning agents, cationic surfactants and polymers, are often limited in their ability to repair and strengthen the hair fibre, while protein-derived actives have been found to enhance the tensile strength of damaged hair.
Daniels, Gabriela   +3 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

An alternative system for damage stability enhancement [PDF]

open access: yes, 2016
There is an ongoing and continuous initiative to improve the survivability of passenger vessels and in the past increasing safety standards have generally been catered for through the use of design(passive) measures. However, this approach is becoming saturated and any such measures to improve damage stability severly erode ship earning potential and ...
Vassalos, Dracos   +2 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Development of a bi-material representative volume element using damaged homogenisation approach

open access: yes, 2013
Most civil engineering structures are formed using a number of materials that are bonded to each other with their surface-to-surface interaction playing key role on the overall response of the structure.
Jelvehpour, Ali, Dhanasekar, Manicka
core   +1 more source

Asymmetric large deformation in deep mining-damaged roadways: mechanism and collaborative control technology by means of destressing-bolting

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
The stability control of mining-damaged roadways remains a fundamental challenge in mining engineering. This study investigates a typical mining-damaged roadway, with its deformation and failure characteristics summarized through field measurements ...
Yongliang Li   +5 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

On the alternative approaches to stability analysis in decision support for damaged passenger ships

open access: yes, 2019
A decision support system with damage stability analysis has been recognized as an important tool for passenger ships. Various software applications have been developed and taken into use over the years, without a direct link to any compelling ...
Ruponen, Pekka   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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