Results 151 to 160 of about 86,173 (293)

Legal Protection of Mental Health for Family Caregivers of People with Mental Disorders: Challenges, Current Situation, and Legislative Response. [PDF]

Psychol Res Behav Manag
Li T, Zheng L, Zhang J.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

From milk to solid: a review and meta-regression analysis on the effects of solid feed on veal calf welfare and abomasal lesions. [PDF]

Front Vet Sci
Cozzi G, Magrin L, Marcon C, Contiero B.
europepmc   +1 more source

Strict Liability in the European Union - Not a United States Analog [PDF]

, 2000
Spacone, Andrew C.
core   +1 more source

Is the Market Classification of Risk Always Efficient? - Evidence from German Third Party Motor Insurance [PDF]

The efficiency of market-determined risk classification in automobile insurance is a lasting matter of controversy. It can be traced back to the 1950s (Muir, 1957) and received broad economic attention in the 1980s when spiralling car insurance premiums ...
Reimund Schwarze, Thomas Wein
core  

The Antitrust Damages Directive: Facilitating Private Damages Actions in the EU? [PDF]

Journal of European Competition Law & Practice, 2019
Barry Rodger, Miguel Sousa Ferro, Francisco Marcos   +2 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Europeans support large carnivore recovery while opposing both further population growth and hunting. [PDF]

Nat Ecol Evol
Chapron G, Epstein Y, Bruskotter JT, López-Bao JV.   +3 more
europepmc   +1 more source

Misfeasance in public office [PDF]

, 1997
Davis, Howard
core  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source