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Delphi Consensus on Attenuated Androgen Use for Long-Term Prophylaxis in Hereditary Angioedema: AURA Project. [PDF]
Background Danazol and other attenuated androgens (AAs) have been a cornerstone of Hereditary Angioedema (HAE) long‐term prophylaxis (LTP) for decades, alongside intravenous plasma‐derived C1INH (pdC1INH). Danazol's potential androgenic effects, however,
Dias de Castro E +3 more
europepmc +3 more sources
Transfusion-related cost offsets and time burden in patients with myelofibrosis on momelotinib vs. danazol from MOMENTUM. [PDF]
Aim: To estimate projected US-based cost and time burden for patients with myelofibrosis and anemia treated with momelotinib compared with danazol. Methods: Cost and time burden were calculated based on the transfusion status of patients in the MOMENTUM ...
Masarova L +11 more
europepmc +4 more sources
No effect of danazol treatment in patients with advanced idiopathic pulmonary fibrosis
Background Telomere dysfunction can underly the development of idiopathic pulmonary fibrosis (IPF), and recent work suggests that patients with telomere syndromes might benefit from treatment with androgens, such as danazol.
T. Hoffman +4 more
semanticscholar +3 more sources
Danazol is a treatment option for autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP). Three patients with AIHA and eight patients with ITP between 2008 and 2022 were enrolled in the Rheumatology Outpatient Clinic of Chang Gung Memorial ...
Hsuen-En Huang +8 more
semanticscholar +3 more sources
Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral ...
J. Mackintosh +19 more
semanticscholar +3 more sources
Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR) cancer.
Ying-Tzu Chang +6 more
semanticscholar +2 more sources

