Results 21 to 30 of about 16,122 (287)

Danazol for heavy menstrual bleeding [PDF]

Cochrane Database of Systematic Reviews, 2002
Heavy menstrual bleeding (HMB) is an important cause of ill health in pre menopausal women. Medical therapy, with the avoidance of possibly unnecessary surgery is an attractive treatment option, but there is considerable variation in practice and uncertainty about the most effective therapy. Danazol is a synthetic steroid with anti-oestrogenic and anti
Heather H Beaumont, Anne Lethaby, C Augood, Kirsten Duckitt   +3 more
openaire   +6 more sources

Hepatocellular Carcinoma in a Noncirrhotic Liver after Long-Term Use of Danazol for Hereditary Angioedema

Case Reports in Oncology, 2014
We report a 57-year-old male who was treated with high-dose danazol for hereditary angioedema for more than 30 years; he developed hepatocellular carcinoma in the absence of cirrhosis.
Soraya Rahal, Marine Gilabert, Pauline Ries, Sandrine Oziel-Taieb, Slimane Dermeche, Jean-Luc Raoul   +5 more
doaj   +2 more sources

Evaluation of a Nanoemulsion Formulation Strategy for Oral Bioavailability Enhancement of Danazol in Rats and Dogs [PDF]

Journal of Pharmacy and Science, 2013
The objective of this study was to determine whether nanoemulsion formulations constitute a viable strategy to improve the oral bioavailability of danazol, a compound whose poor aqueous solubility limits its oral bioavailability.
Harikrishna Devalapally, Svitlana Silchenko, Feng Zhou, Jessica McDade, Galina Goloverda, Albert J. Owen, Ismael J. Hidalgo   +6 more
openalex   +2 more sources

Herediter anjioödemde kısa dönem danazol profilaksisi ile implant tedavisi: Vaka raporu

Selcuk Dental Journal, 2019
Herediter anjio ödem (HAÖ), C1 esteraz inhibitör proteininin konjenital eksikliğine bağlı olarak meydana gelen, nadir gözlenen, otozomal dominant bir hastalıktır. HAÖ atakları, spontan veya bir travmaya bağlı olarak, ekstremitelerde, yüzde, göğüste, hava
Zeynep Burçin Gönen, Fatma Doğruel, Canay Yılmaz Asan, Leylagül Kaynar, Mustafa Çetin   +4 more
doaj   +3 more sources

Danazol improves thrombocytopenia in HCV patients treated with peginterferon and ribavirin

Annals of Hepatology, 2011
Background. Thrombocytopenia is a common hematologic disorder observed in patients with chronic hepatitis C virus (HCV) infection. Combined peginterferon (PEG-INF) and ribavirin treatment may exacerbate thrombocytopenia in patients with HCV.Objective ...
Guillermo Cabrera Álvarez, Diana Gόmez-Galicia, Lourdes Rodríguez-Fragoso, Vicente Madrid Marina, Luis Cañedo Dorantes, Miguel Sánchez-Alemán, Nahum Méndez-Sánchez, Jorge Reyes Esparza   +7 more
doaj   +2 more sources

Transfusion-related cost offsets and time burden in patients with myelofibrosis on momelotinib vs. danazol from MOMENTUM. [PDF]

Future Oncol
Aim: To estimate projected US-based cost and time burden for patients with myelofibrosis and anemia treated with momelotinib compared with danazol. Methods: Cost and time burden were calculated based on the transfusion status of patients in the MOMENTUM ...
Masarova L, Verstovsek S, Liu T, Rao S, Sajeev G, Fillbrunn M, Simpson R, Li W, Yang J, Le Lorier Y, Gorsh B, Signorovitch J.   +11 more
europepmc   +2 more sources

Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat. [PDF]

Front Pharmacol
BackgroundDanazol is regularly used as a prophylactic treatment in patients with Hereditary angioedema due to C1-inhibitor deficiency (HAE-C1INH). However, this drug is characterized by a risk of drug-drug interactions (DDIs).
Zanichelli A, Cattaneo D, Gidaro A, Senter R, Arcoleo F, Accardo P, Bignardi D, Borrelli P, Colangelo C, De Pasquale T, Firinu D, Perego F, Triggiani M, Spadaro G, Cogliati C, Bizzi E, Popescu Janu V, Guarino MD, Quattrocchi P, Brussino L, Rossi O, Triggianese P, Agolini S, Giardino F, Montinaro V, Cancian M.   +25 more
europepmc   +2 more sources

Application of different methods to predict the lipophilicity parameter of danazol [PDF]

Farmacja Polska, 2021
The aim of this study was to evaluate the applicability of both methods, i.e. reversed-phase thin-layer chromatography (RP-TLC) and high-performance thin-layer chromatography (RP-HPTLC), and computational algorithms to determine the lipophilicity ...
Małgorzata Dołowy, Rafał Sochacki
doaj   +1 more source

Danazol in Refractory Autoimmune Hemolytic Anemia or Immune Thrombocytopenia: A Case Series Report and Literature Review

Pharmaceuticals, 2022
Danazol is a treatment option for autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP). Three patients with AIHA and eight patients with ITP between 2008 and 2022 were enrolled in the Rheumatology Outpatient Clinic of Chang Gung Memorial ...
Hsu-En Huang, Ko-Ming Lin, Jing-Chi Lin, Yu-Ting Lin, Hsiao-Ru He, Yu-Wei Wang, Shan-Fu Yu, Jia-Feng Chen, Tien-Tsai Cheng   +8 more
doaj   +1 more source

Clinical Presentation and Management of Mastalgia: A Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Recurring mastalgia, non-cyclical mastalgia and nonspecific extra-mammary pain are usually categorised as breast pain. Aim: To determine the most usual aetiology of mastalgia and its response to management modalities like topical Non ...
TG Raghu
doaj   +1 more source