Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model. [PDF]
Front Endocrinol (Lausanne)BackgroundRecently, central precocious puberty (CPP) is becoming a major public health concern worldwide due to its enhanced prevalence. Traditional Chinese medicine (TCM) compounds offer unique therapeutic advantages for treating this condition, and ...
Zha Z +10 more
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Case Reports in Oncology, 2014 We report a 57-year-old male who was treated with high-dose danazol for hereditary angioedema for more than 30 years; he developed hepatocellular carcinoma in the absence of cirrhosis.
S. Rahal +5 more
semanticscholar +3 more sources
Danazol: An Effective and Underutilised Treatment Option in Diamond-Blackfan Anaemia [PDF]
Case Reports in Hematology, 2019 Diamond-Blackfan anaemia (DBA) is a rare congenital red cell aplasia that presents in infancy. The exact molecular mechanism of ineffective erythropoiesis and red cell aplasia remains unclear, rendering targeted therapy elusive. The mainstay treatment of
Kern Y. Chai +2 more
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A Rare Case of Systemic Cystic Angiomatosis in an Elderly Female Initially Misdiagnosed as Vascular Neoplasm: A Case Report and Literature Review. [PDF]
J Orthop Case RepIntroduction: Systemic cystic angiomatosis is an exceedingly rare condition characterized by widespread cystic vascular lesions involving multiple organs. Its clinical presentation can be non-specific, often leading to diagnostic challenges.
Mohan S +5 more
europepmc +2 more sources
Application of different methods to predict the lipophilicity parameter of danazol [PDF]
Farmacja Polska, 2021 The aim of this study was to evaluate the applicability of both methods, i.e. reversed-phase thin-layer chromatography (RP-TLC) and high-performance thin-layer chromatography (RP-HPTLC), and computational algorithms to determine the lipophilicity ...
Małgorzata Dołowy, Rafał Sochacki
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Autoimmune Thrombocytopenia Treated by Low-Dose Splenic Irradiation Followed by Splenectomy in a Patient With Systemic Lupus Erythematosus. [PDF]
Clin Case RepABSTRACT Severe autoimmune thrombocytopenia (ATP) in systemic lupus erythematosus (SLE) patients can be life‐threatening when refractory to standard treatments. Low‐dose splenic irradiation (LDSI) can provide temporary platelet recovery before definitive splenectomy.
Hanaoka R.
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Formulation of a danazol cocrystal with controlled supersaturation plays an essential role in improving bioavailability. [PDF]
Molecular Pharmaceutics, 2013 S. Childs +2 more
semanticscholar +2 more sources
Future Oncology, 2021 Hallmark features of myelofibrosis (MF) are cytopenias, constitutional symptoms and splenomegaly. Anemia and transfusion dependency are among the most important negative prognostic factors and are exacerbated by many JAK inhibitors (JAKi).
S. Verstovsek +20 more
semanticscholar +1 more source
Plants, 2021 Anemarrhenae rhizome and Phellodendri cortex have historically been used for the treatment of precocious puberty (PP) in oriental medicine. Our study aimed to evaluate the effect of APE, a mixture of the extracts from these herbs, against danazol-induced
Kyeong Ri Kim +9 more
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Preventive Effects of <i>Eclipta prostrata</i> and <i>Hordeum vulgare</i> Extract Complex on Precocious Puberty in Danazol- and High-Fat Diet-Induced Rat Models. [PDF]
Int J Mol SciKim YS, Eom T, Kim Y, Rhee J, Kim H.
europepmc +3 more sources