Results 11 to 20 of about 4,542,015 (210)

IMPACTO DO SILENCIAMENTO DAS PROTEÍNAS RHOA E RHOC NA NA AQUISIÇÃO DE DANOS AO DNA E MORTE DE CÉLULAS MIELOIDES U937 TRATADAS COM UVC

open access: yesHematology, Transfusion and Cell Therapy
Introdução: RhoA e RhoC são proteínas RHO GTPases homólogas que desempenham papéis cruciais na regulação de processos celulares, incluindo a apoptose e a resposta ao dano no DNA. Compreender as funções específicas dessas proteínas em resposta ao estresse
SSC Sampaio   +6 more
doaj   +2 more sources

ANÁLISE IN VITRO DO DANO AO DNA EM PACIENTES COM DIAGNÓSTICO OU SUSPEITA DE HEMOCROMATOSE HEREDITÁRIA E CORRELAÇÕES COM DESFECHOS CLÍNICOS

open access: yesHematology, Transfusion and Cell Therapy, 2020
J.C. Fontana   +8 more
doaj   +2 more sources

Associação entre escore de gravidade, níveis inflamatórios e dano no DNA em pacientes na terapia intensiva

open access: yesRevista de Epidemiologia e Controle de Infecção, 2020
Justificativa e Objetivos: A Unidade de Terapia Intensiva (UTI) é responsavel pelo tratamento de pacientes críticos. A sua monitorização contínua pode melhorar da qualidade dos cuidados prestados.
Andriela Vieceli Mattje   +7 more
doaj   +1 more source

Synadenium umbellatum: citotoxicidade e danos ao DNA de células da medula óssea de camundongos [PDF]

open access: yesRevista Brasileira de Ciências Farmacêuticas, 2007
In the present study we investigated, in vitro and in vivo, the cytotoxic and mutagenic potential of the Synadenium umbellatum ethanolic extract (SUEE) on the bone marrow cells of mice. In vitro cytotoxicity was assayed incubating bone marrow cells with different concentrations (40-0.312 mg/mL) of SUEE for 12, 24 or 48 h using the MTT tetrazolium ...
Valadares, Marize Campos   +2 more
openaire   +3 more sources

Enhancement of Executive Functions but Not Memory by Multidomain Group Cognitive Training in Patients with Parkinson’s Disease and Mild Cognitive Impairment: A Multicenter Randomized Controlled Trial

open access: yesParkinson's Disease, Volume 2020, Issue 1, 2020., 2020
Background. Meta‐analyses have demonstrated cognitive training (CT) benefits in Parkinson’s disease (PD) patients. However, the patients’ cognitive status has only rarely been based on established criteria. Also, prediction analyses of CT success have only sparsely been conducted. Objective.
Elke Kalbe   +14 more
wiley   +1 more source

Effects of primaquine and chloroquine on oxidative stress parameters in rats

open access: yesAnais da Academia Brasileira de Ciências, 2015
Primaquine and chloroquine are used for the treatment of malaria; evidence from the literature suggests that these drugs may induce oxidative stress.
FRANCIANNE GIOVANELLA   +14 more
doaj   +1 more source

Expressão de Genes relacionados às Vias de Reparo de Danos em Fita Dupla no DNA em Pacientes com Síndrome Mielodisplásica

open access: yesRevista Brasileira de Cancerologia, 2016
Introdução: A síndrome mielodisplástica (SMD) é uma doença clonal da célula progenitora hematopoiética apresentando um processo patogênico associado a um evento genético inicial nas células-tronco (lesão no DNA) que leva ao aparecimento de um clone ...
Howard Lopes Ribeiro Junior   +1 more
doaj   +1 more source

Effect of methionine load on homocysteine levels, lipid peroxidation and DNA damage in rats receiving ethanol

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2009
Changes in the metabolism of methionine can cause hyperhomocysteinemia, inducing a triad of atherosclerosis, hypertension, and increased oxidative stress. The generation of free radicals and oxidative damage to DNA is important in the liver damage caused
Alceu Afonso Jordao Júnior   +4 more
doaj   +1 more source

CURCUMIN IN COMBINATION WITH TRIPLE THERAPY REGIMES AMELIORATES OXIDATIVE STRESS AND HISTOPATHOLOGIC CHANGES IN CHRONIC GASTRITIS-ASSOCIATED HELICOBACTER PYLORI INFECTION

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND Helicobacter pylori (H. pylori) gastric infection is a main cause of inflammatory changes and gastric cancers. OBJECTIVE The aim of this study was finding the effects of curcumin on oxidative stress and histological changes in chronic ...
Arezu JUDAKI   +4 more
doaj   +1 more source

The importance of oxygen free radicals in the etiopathogenesis of diversion colitis in rats A importância dos radicais livres de oxigênio na etiopatogenia da colite de exclusão em ratos

open access: yesActa Cirúrgica Brasileira, 2010
PURPOSE: Quantify the levels of oxidative DNA damage of epithelial colon cells comparing segments with and without fecal stream. METHODS: Sixty Wistar rats were subjected to deviation of fecal stream by proximal colostomy and a distal mucosal fistula ...
Carlos Augusto Real Martinez   +5 more
doaj   +1 more source

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