Results 241 to 250 of about 14,850 (297)

Hexamorphism of Dantrolene: Insight into the Crystal Structures, Stability, and Phase Transformations

, 2021
Dantrolene represents yet another interesting example of abundant molecular crystal polymorphism existing in at least six different neat polymorphs, three of which can be obtained via crystallizati...
Artis Kons, A. Mishnev, T. A. Mukhametzyanov, Alexey V. Buzyurov, S. Lapuk, A. Be̅rziṇš   +5 more
semanticscholar   +1 more source

Identification of enzymes responsible for dantrolene metabolism in the human liver: A clue to uncover the cause of liver injury

Biochemical Pharmacology, 2018
Tatsuki Fukami, Jeffrey P Jones, Tsuyoshi Taniguchi   +2 more
exaly   +2 more sources

DANTROLENE INDUCES MITIGATION OF MYOCARDIAL ISCHEMIA-REPERFUSION INJURY BY RYANODINE RECEPTOR INHIBITION.

Seminars in Thoracic and Cardiovascular Surgery, 2021
The impairment of intracellular calcium homeostasis plays an essential role during ischemia-reperfusion injury. Calcium release from sarcoplasmic reticulum which is triggered by myocardial ischemia is mainly mediated by ryanodine receptors.
I. Samiotis, N. Papakonstantinou, P. Dedeilias, I. Vasileiadis, A. Papalois, S. Deftereos, A. Kotanidou   +6 more
semanticscholar   +1 more source

Dantrolene

Drugs, 2012
exaly   +2 more sources

Different Stability Indicating Chromatographic Methods for Specific Determination of Paracetamol, Dantrolene Sodium, Their Toxic Impurities, and Degradation Products.

Biomedical chromotography, 2019
A well-known analgesic [paracetamol (PAR)] and skeletal muscle relaxant [Dantrolene sodium (DNS)] have been analyzed without interference from their toxic impurities and degradation products. The studied PAR impurities are the genotoxic and nephrotoxic p-
N. Abdelwahab, M. M. Abdelrahman, John M Boshra, A. A. Taha   +3 more
semanticscholar   +1 more source

Dantrolene sodium increases calcium binding by human recombinant cardiac calsequestrin and calcium loading by sheep cardiac sarcoplasmic reticulum

Acta Physiologica, 2019
Dantrolene interacts with ryanodine receptors in skeletal and cardiac muscle affecting sarcoplasmic reticulum calcium release. Since dantrolene is lipophilic it could also affect intra‐sarcoplasmic reticulum calcium handling proteins such as ...
Christine M. Loescher, L. M. Gibson, D. Stephenson   +2 more
semanticscholar   +1 more source

Effects of chronic intranasal dantrolene on nasal mucosa morphology in mice.

European Review for Medical and Pharmacological Sciences, 2022
B. Jiang, Y. Shi, M. B. Abou, L. Xu, G. Liang, H. Wei   +5 more
semanticscholar   +1 more source

Hyperkalemia after Dantrolene and Verapamil-Dantrolene Administration in Dogs

Anesthesia & Analgesia, 1988
The concurrent administration of dantrolene and verapamil has the theoretical advantage of being more efficacious than dantrolene alone in the treatment of malignant hyperthermia. However, the combination has been reported to cause fatal hyperkalemia in pigs.
A C, San Juan, K C, Wong, J D, Port
openaire   +2 more sources

Dantrolene

Reactions Weekly, 2021
openaire   +2 more sources

Dantrolene repurposed to treat sepsis or septic shock and COVID-19 patients.

European Review for Medical and Pharmacological Sciences, 2021
H. Wei, G. Liang, R. Vera
semanticscholar   +1 more source