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Hepatitis Associated with Dantrolene Sodium
Annals of Internal Medicine, 1976Excerpt Dantrolene sodium, a hydantoin derivative that became commercially available in 1974, has been used to decrease skeletal muscle spasticity in patients with various disorders (1-3).
ROBERT M. OGBURN +2 more
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Neuroleptic Malignant Syndrome: Response to Dantrolene Sodium
Annals of Internal Medicine, 1983Abstract The neuroleptic malignant syndrome is an uncommon and potentially lethal complication of treatment with antipsychotic medication (1).
D C, May +4 more
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Management of lethal catatonia with dantrolene sodium
Critical Care Medicine, 1991Lethal catatonia, a life-threatening, febrile neuropsychiatric disorder, was reported before the introduction of modern psychopharmacologic treatment. Kraepelin (1) discussed this disorder as a syndrome that comprises a characteristic cluster of symptoms, such as catalepsy, negativism, posturing ...
E, Van de Kelft +4 more
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Dantrolene sodium and fatigue of long duration
Muscle & Nerve, 1992AbstractA long‐lasting imparment of muscular force generation follows fatiguing exercise (fatigue of long duration), the physiological basis of which is not well understood. To investigate the role of reduced calcium release in longlasting fatigue, we examined the effects of dantrolene sodium, which selectively decreases calcium release from the ...
R S, Moussavi, S L, Lehman, R G, Miller
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Drugs, 1977
Dantrolene sodium or dantrolene1 is 1([5-(nitrophenyl)furfurylidend] amino) hydantoin sodium hydrate. It is indicated for use in chronic disorders characterised by skeletal muscle spasticity, such as spinal cord injury, stroke, cerebral palsy and multiple sclerosis.
R M, Pinder +3 more
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Dantrolene sodium or dantrolene1 is 1([5-(nitrophenyl)furfurylidend] amino) hydantoin sodium hydrate. It is indicated for use in chronic disorders characterised by skeletal muscle spasticity, such as spinal cord injury, stroke, cerebral palsy and multiple sclerosis.
R M, Pinder +3 more
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ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF DANTROLENE AND SODIUM DANTROLENE
Chemischer Informationsdienst, 1985AbstractDer Aldehyd (I) reagiert mit Aminohydantoin (II) zu Dantrolen (III), aus dem mit Natrium‐methylat das Natrium‐Salz (IV) erhalten wird.
A. F. OLEINIK +4 more
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Phenelzine Overdose Treated With Dantrolene Sodium
JAMA: The Journal of the American Medical Association, 1986THE INGESTION of a monoamine oxidase (MAO) inhibitor can induce a complex array of hypermetabolic signs, including hyperpyrexia, tachycardia, generalized muscle rigidity, tachypnea, metabolic acidosis, hypoxemia, and hypercapnia 1 (J. W. Katalavis, MD, oral communication, November 1984).
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Dantrolene sodium: urinary metabolites and hepatotoxicity.
Research communications in chemical pathology and pharmacology, 1983Dantrolene is metabolized by the hepatic MFO system to hydroxydantrolene which is conjugated with glucuronic acid or with sulfate. Dantrolene is also metabolized by nitroreductase to aminodantrolene. The aminodantrolene inhibits the hepatic MFO system.
T H, Arnold +3 more
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