Results 51 to 60 of about 1,064,868 (260)
Dantrolene sodium may not be effective in the treatment of status epileptics
Rinshō shinkeigaku Clinical neurology, 2012 Shutaro Takashima
openalex +3 more sources
A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child
Journal of Pediatric Emergency and Intensive Care Medicine, 2018 Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine.
Ümüt Altuğ +5 more
doaj +1 more source
Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx. [PDF]
, 2016 Retinitis pigmentosa (RP) is a degenerative retinal disease leading to photoreceptor cell loss. In 2011, our group identified the synthetic progesterone ‘Norgestrel’ as a potential treatment for RP.
Byrne, Ashleigh M. +5 more
core +1 more source
Pharmacotherapy of Spasticity in Children With Cerebral Palsy
Journal of the Formosan Medical Association, 2011 Spasticity is a common disability in children with cerebral palsy. Pharmacological and non-pharmacological treatments, including physical therapy, occupational therapy, orthotics, rhizotomy, and orthopedic surgery, all play important roles in the ...
Chia-Ying Chung +2 more
doaj +1 more source
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper [PDF]
, 2016 BACKGROUND AND OBJECTIVES: Treatment of spasticity poses a major challenge given the complex clinical presentation and variable efficacy and safety profiles of available drugs. We present a systematic review of the pharmacological treatment of spasticity
Comi, G +8 more
core +1 more source
Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits [PDF]
, 2018 Hypertrophic cardiomyopathy (HCM) is a primary disorder of contractility in heart muscle. To gain mechanistic insight and guide pharmacological rescue, this study models HCM using isogenic pairs of human induced pluripotent stem cell-derived ...
Barriales-Villa, Roberto +13 more
core +2 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Ryanodine receptors: physiological function and deregulation in Alzheimer disease [PDF]
, 2014 BackgroundHealth-care professionals have a responsibility to be attentive to patients’ adherence behavior but it could be difficult to identify poor adherence in the context of clinical practice.
Axelsson, Malin +3 more
core +2 more sources
Advanced Science, Volume 13, Issue 1, 5 January 2026.Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source