Results 71 to 80 of about 1,064,868 (260)
Bile acids activate ryanodine receptors in pancreatic acinar cells via a direct allosteric mechanism [PDF]
, 2015 The earliest critical event of pancreatitis is a long lasting high amplitude rise of intracellular Ca(2+) concentration of the acinar cell, which can be triggered by high concentration of bile acids.
Almássy, János +4 more
core +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang +21 more
wiley +1 more source
Analysis of the flavonoid component of bioactive New Zealand mānuka (Leptospermum scoparium) honey and the isolation, characterisation and synthesis of an unusual pyrrole [PDF]
, 2013 The flavonoid components of New Zealand mānuka (Leptospermum scoparium) honey have been quantified in a series of 31 honeys of varying non-peroxide antibacterial activity to clarify discrepancies between previous studies reported in the literature. Total
Alber, Dagmar G. +5 more
core +2 more sources
Advanced Intelligent Systems, Volume 7, Issue 10, October 2025.The integration of sensing elements in bioengineered actuators is key to obtain real‐time information about their performance and further control/automation. By coupling flexible organic field‐effect transistor to a skeletal muscle actuator we demonstrate the feasibility to record in real‐time its contractile behavior when stimulated by electrical ...
Stefano Lai +5 more
wiley +1 more source
Computational analysis of calcium signaling and membrane electrophysiology in cerebellar Purkinje neurons associated with ataxia [PDF]
, 2012 BACKGROUND: Mutations in the smooth endoplasmic reticulum (sER) calcium channel Inositol Trisphosphate Receptor type 1 (IP3R1) in humans with the motor function coordination disorders Spinocerebellar Ataxia Types 15 and 16 (SCA15/16) and in a ...
Leslie M Loew, Sherry-Ann Brown
core +2 more sources
Food Science &Nutrition, Volume 13, Issue 9, September 2025.We conducted a comprehensive search of publicly available databases. The main focus is to investigate the pharmacological effects and mechanisms of Portulaca oleracea L. in the treatment of musculoskeletal disorders. This study aims to provide a reference for further research into the active components of this plant. ABSTRACT Portulaca oleracea L. is a
Yanxin Li +8 more
wiley +1 more source
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication [PDF]
, 2014 Paraoxon (POX) is an active metabolite of organophosphate (OP) pesticide parathion that has been weaponized and used against civilian populations. Exposure to POX produces high mortality.
Blair, Robert E. +4 more
core +2 more sources
Pain Practice, Volume 25, Issue 7, September 2025.ABSTRACT Introduction Discogenic low back pain can be severely disabling, clinically challenging to diagnose, and expensive to treat. Disc degeneration is characterized by disc dehydration, which diminishes the ability of the disc to distribute pressure, making it more susceptible to damage, and leading to annular tears, fissures, and a higher ...
Wouter K. M. van Os +6 more
wiley +1 more source
Antidote Stocking at Hospitals in North Palestine [PDF]
, 2007 Objective: The purpose of this study was to determine the availability and adequacy of antidote stocking at hospitals in north Palestine based on published guidelines for antidote stocking.
Al-Jabi W, Samah +3 more
core +1 more source