Results 101 to 110 of about 282,531 (251)

A Confucian Perspective on Public Health Ethics

Bioethics, EarlyView.
ABSTRACT Debates in public health ethics have been dominated by the assumptions of Western liberalism: a priority given to liberty and autonomy over other values, an individualistic view of social ontology, a focus on personal responsibility, a minimal set of obligations (only created through consent), and a marginalization of social, cultural, and ...
Kathryn Muyskens, Angus Dawson
wiley   +1 more source

D‐amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose D‐amino acid oxidase (DAO) has been developed as a chemogenetic tool, to precisely manipulate redox levels in tissues and cells by generating H2O2 in the presence of D‐amino acids. The enzyme's significant oxygen consumption during H2O2 production may influence cellular oxygen levels.
Wiebke Maurer, Anke Zieseniss, Vamsi Priya Vikram, Yamin Chen, Laura Bauer, Annette Hillemann, Peter Rehling, Maithily S. Nanadikar, Diane de Zélicourt, Vartan Kurtcuoglu, Dörthe M. Katschinski   +10 more
wiley   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

Dual-ligand engineered exosome regulates WNT signaling activation to promote liver repair and regeneration

Nature Communications
WNT signaling is an essential pathway regulating tissue morphogenesis and regeneration. However, harnessing the pathway for regenerative medicine has been challenging due to the lack of approaches to identify and deliver specific WNT ligands to the ...
Lingyan Yang, Shixiang Wang, Zhiping Qiao, Yue Liu, Xu Wang, Liying Liu, Chunfang Yang, Jiying Ding, Miao Lei, Jiayi Zheng, Wenxiang Hu, Ye-guang Chen, Yun-Shen Chan   +12 more
doaj   +1 more source

Rethinking the ‘Defeminization of Agriculture’: Land Consolidation and Crop Diversification in Vietnam's Red River Delta

Development and Change, EarlyView.
ABSTRACT Over the past two decades, agricultural restructuring in Vietnam — driven by land consolidation, crop diversification and modernization — has shifted farming from labour‐intensive to capital‐intensive production. This article argues that agrarian change in Vietnam has not simply resulted in the marginalization of women, a finding that ...
Nga Dao, Quang Phung
wiley   +1 more source

How Teachers See It: Understanding Young Learners’ Engagement in Primary L2 Classrooms

International Journal of Applied Linguistics, EarlyView.
ABSTRACT This study investigated primary school teachers’ views and the basis for assessing young learners’ engagement in second language classrooms. Using a sequential mixed‐methods design, it analyzed interviews (n = 10) and surveys (n = 134) from teachers of learners in Grades 3–5 (aged 8–10 years old) across 102 public primary schools in Vietnam ...
Phung Dao, Trang Le Diem Bui
wiley   +1 more source

Attainment Pairing Effects on Cognitive Conflict in Technology‐enhanced EFL Cooperative Tasks

International Journal of Applied Linguistics, EarlyView.
ABSTRACT This study examines how attainment pairing (high‐high versus high‐low versus low‐low attainment) impacts English as a Foreign Language (EFL) learner engagement during technology‐enhanced cooperative writing tasks. Seventy‐eight Chinese university learners formed 39 dyads (13 pairs per group) via Tencent Meeting.
Ying Liu, Allen Thurston
wiley   +1 more source

Compassionate Digital Innovation: A Pluralistic Perspective and Research Agenda

Information Systems Journal, EarlyView.
ABSTRACT Digital innovation offers significant societal, economic and environmental benefits but is also a source of profound harms. Prior information systems (IS) research has often overlooked the ethical tensions involved, framing harms as ‘unintended consequences’ rather than symptoms of deeper systemic problems.
Raffaele F. Ciriello, Lars Mathiassen, Marten Risius, Marc Cheong, Helana Scheepers, Emmanuelle Vaast   +5 more
wiley   +1 more source

Poemas de Bei Dao

Estudios de Asia y África, 1990
Traducción del chino: Ding ZixiongVersión en español: Mariela ÁlvarezIntroducción: Romer ...
Romer Cornejo Bustamante, tr. Ding Zixiong, Mariela Álvarez   +2 more
doaj  

An iterated greedy‐based metaheuristic with local search for the rank pricing problem

International Transactions in Operational Research, EarlyView.
Abstract The rank pricing problem involves determining optimal prices for a set of products while accounting for customers' budgets and preferences. This study develops an iterated greedy‐based metaheuristic to efficiently solve this problem. The core idea is to generate a sequence of solutions by iteratively applying destruction and reconstruction ...
Herminia I. Calvete, Carmen Galé, Aitor Hernández, José A. Iranzo   +3 more
wiley   +1 more source