Results 201 to 210 of about 195,859 (249)

circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Circular RNAs (circRNAs) are emerging as key regulators of gene expression, synaptic plasticity, and neuronal function in Alzheimer's disease (AD). Here, we characterize the biological actions of circPDE4B, a highly expressed circRNA markedly reduced in AD. METHODS circPDE4B knockdown in neuronal progenitor cells was combined with
Sambhavi Puri, Sophie J. F. van der Spek, Mintao Lin, Zihan Wang, Jacob Porter, Junming Hu, Liyuan Hu, Alejandro N. Rondón‐Ortiz, Alexander Knyshov, Jenna L. Libera, Scott E. Counts, Debomoy K. Lahiri, Julia TCW, Andrew Emili, Xiaoling Zhang, Benjamin Wolozin   +15 more
wiley   +1 more source

ZmMYB127 controls maize endosperm filling via dual-transcriptional regulation to improve grain yield and quality. [PDF]

Nat Plants
Shi J, Li Z, Wang Z, Pan S, Wu X, Wang X, Ye Y, Xu Z, He J, Zhang Z.   +9 more
europepmc   +1 more source

Chemical Profiling and Biological Activity of Copaiba Oil‐Resin Samples and Development of HPLC‐DAD Method for the Analysis of β‐Caryophyllene

Biomedical Chromatography, Volume 40, Issue 5, May 2026.
ABSTRACT The Copaifera species are traditionally used for their anti‐inflammatory, antiseptic and healing properties. The objective of this study was to compare the chromatographic profiles of seven samples of copaiba oil‐resin with respect to chromatographic and physicochemical properties and to evaluate their biological activities.
Gabriel de A. P. Graça, Cláudia G. Silva, Denise de O. Scoaris, Juliana Rodrigues de Vasconcelos, André Santos Alkimim, Vanessa C. F. Mosqueira, Luciana S. Salomon, Pietra Piotto Marcellini, Isabelle Renata Martins da Silva, Janete S. C. Santos, Andreia Fonseca Silva, Carolina P. S. Moreira, Júlio C. D. Lopes, Vera L. de Almeida   +13 more
wiley   +1 more source

Subphenotyping hypotension in early sepsis: A physiology-guided therapeutic approach. [PDF]

Ann Intensive Care
Sanchez E C, Teboul JL.
europepmc   +1 more source

A pleiotropic “stretch” phenotype is associated with metaxylem vessel element length, axial hydraulic conductance, root elongation, water utilization, and drought adaptation in maize

Crop Science, Volume 66, Issue 3, May/June 2026.
Abstract We tested the hypothesis that metaxylem phenotypes influence drought adaptation in maize (Zea mays L.) through in silico modeling and empirical studies under water deficit in controlled environments and in the field. Substantial genotypic variation for metaxylem vessel element length (MVEL) was observed. Longer MVEL was correlated with reduced
Christopher F. Strock, Cody L. DePew, Jagdeep S. Sidhu, Tianyu Xu, Jonathan P. Lynch   +4 more
wiley   +1 more source

Beyond the Mean: The Dynamic Fingerprint of Vasoplegia in Septic Shock. [PDF]

Indian J Crit Care Med
Singh AP, Govil D.
europepmc   +1 more source

Geomorphic Effectiveness of an Extreme Flood in a Mountain River: Evidence From Pre‐ and Post‐Event Surveys in a Subtropical Region of Southern Brazil

Hydrological Processes, Volume 40, Issue 5, May 2026.
The extreme flooding of April 2024 caused a complete “geomorphic reset”, resulting in a 24% widening of the channel and a transition to critical or supercritical flow regimes. The energy of the event broke through the stable armouring layer, reducing the armouring ratio from 7.9 to 4.9 and intensely removing fine sediments from the subsurface.
Gabriel Augusto Feyh, Jean Paolo Gomes Minella, Eno Darci Saatkamp, Lidiane Buligon, Gustavo Henrique Merten, Felipe Bernardi, Cristiano Carvalho da Silva, Angelo Garcia Costa, Alice Prates Bisso Dambroz   +8 more
wiley   +1 more source

<i>ZmbHLH81</i> Enhances Maize Drought Tolerance via Direct Transcriptional Activation of ABA Signaling and ROS Scavenging Genes. [PDF]

Int J Mol Sci
Zhang N, Wang G, Zhang X, Zhao W, Shi Q, Fan X, Lin N, Song S.   +7 more
europepmc   +1 more source

Prevalence of disorders of gut–brain‐interaction in pediatric patients with in‐remission inflammatory bowel disease: An Italian multicenter study

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1171-1177, May 2026.
Abstract Objectives Pediatric patients with in‐remission inflammatory bowel disease (IBD) often report persistent gastrointestinal symptoms, suggesting a potential overlap with disorders of gut–brain‐interaction (DGBIs). While DGBIs affect up to 40% of the general population, their prevalence in quiescent IBD children remains limited.
Giovanna Quatrale, Niccolo’ Chirico, Luigi Colecchia, Giuseppe Stella, Francesco Proli, Pietro Pisano, Erminia Romeo, Paola De Angelis, Licia Pensabene, Giovanni Marasco, Giovanni Di Nardo, Giovanni Barbara, Antonio Gasbarrini, Franco Scaldaferri, Valentina Giorgio   +14 more
wiley   +1 more source