Results 11 to 20 of about 2,485 (155)

Adherence to the Dapivirine Vaginal Ring Among Cisgender Women in Africa: Protocol for a Systematic Review and Meta‐Analysis [PDF]

Health Science Reports
Background and Aims Despite the availability of HIV preventive measures, new HIV infections are still on the rise. The Dapivirine Vaginal Ring (DVR) is a silicone circular ring that continuously distributes 25 mg of Dapivirine into a woman's vagina for ...
Roseline Dzekem Dine, Giulia Muraca, Behnam Sadeghirad, Lawrence Mbuagbaw   +3 more
doaj   +3 more sources

PrEP choice in the real world: Results of a prospective cohort study describing uptake and use patterns of oral PrEP and the dapivirine vaginal ring among women in sub‐Saharan Africa [PDF]

Journal of the International AIDS Society
Introduction HIV incidence remains high among women in Africa, especially adolescent girls and young women (AGYW), despite existing oral pre‐exposure prophylaxis (PrEP) programmes.
Virginia A. Fonner, Elizabeth Irungu, Mark Conlon, Carolyne A. Akello, Emily Gwavava, Kevin K'Orimba, Nicolette P. Naidoo, Patriciah Jeckonia, Imelda Mahaka, Saiqa Mullick, Mamatli Chabela, Roisin Drysdale, Jacqueline Kabongo, Millicent Kiruki, Ivan Segawa, Munyaradzi Dobbie, Nthuseng Marake, Peter Mudiope, Hasina Subedar, Rose Wafula, Andrew Kazibwe, Jason Reed, Katharine Kripke, Douglas Taylor, Mu‐Tien Lee, Glory Chidumwa, Adatia Chivafa, Ramatsoai Soothoane, Margaret Eichleay, Ashley Mayo, Courtney McGuire, Tara McClure, Tatenda Yemeke, Kristine Torjesen, the CATALYST study team   +34 more
doaj   +3 more sources

“People have options”: a qualitative study of experiences and influences of PrEP choice among women in South Africa [PDF]

Journal of the International AIDS Society
Introduction Long‐acting injectable cabotegravir and dapivirine vaginal ring were recently introduced in South Africa through demonstration projects, providing additional HIV prevention options to oral pre‐exposure prophylaxis (PrEP). PrEP choice marks a
Siphokazi Dada, Faith Mary Musvipwa, Fatima Abegail Cholo, Melanie Pleaner, Alison Kutywayo, Vusile Butler, Catherine Elizabeth Martin, Saiqa Mullick   +7 more
doaj   +3 more sources

User and healthcare provider early experiences with the PrEP ring: a quantitative study on the introduction of a new PrEP method in Eswatini [PDF]

Journal of the International AIDS Society
Introduction Eswatini prepared for the national rollout of HIV pre‐exposure prophylaxis (PrEP) choice through a mixed‐method demonstration study introducing the PrEP dapivirine vaginal ring in 12 Ministry of Health‐supported sites. The Eswatini PrEP Ring
Anita Hettema, Siphesihle Shongwe, Haley Sisel, Mxolisi Khumalo, Ncediso Gama, Nolwazi Khanyile, Buyile Mahlalela, Sindy Nana Matse, Jill M. Peterson   +8 more
doaj   +3 more sources

HIV‐1 testing in the context of expanding PrEP modalities [PDF]

Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Abstract Introduction Multiple effective antiretroviral‐based pre‐exposure prophylaxis (PrEP) modalities for HIV‐1 prevention are now available or under investigation but their safe rollout requires implementable HIV‐1 testing strategies that accurately identify rare cases of HIV‐1 acquisition.
Urvi M. Parikh, Jana L. Jacobs, Njambi Njuguna, Kristine Torjesen, John W. Mellors   +4 more
wiley   +2 more sources

Expanding access to a choice‐based multi‐method PrEP market for HIV prevention [PDF]

J Int AIDS Soc
Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Nicolette P. Naidoo, James Ayieko, Virginia A. Fonner   +2 more
wiley   +2 more sources

Multifaceted impact of HIV inhibitor dapivirine on triple negative breast cancer cells reveals potential entities as targets for novel therapy [PDF]

Scientific Reports
Breast cancer is the most common cancer in women worldwide. Many breast cancers originate from the cells lining the milk duct and some become invasive. Breast cancer lacking estrogen, progesterone receptors (ER-, PR-) and epidermal growth factor receptor
Ketki Patil, Elizabeth Johnston, Joseph Novack, Garrett Wallace, Michelle Lin, S. Balakrishna Pai   +5 more
doaj   +2 more sources

Southern African HIV Clinicians Society guideline on pre-exposure prophylaxis to prevent HIV [PDF]

Southern African Journal of HIV Medicine
No Abstract available.
Pippa Macdonald, Gonasagrie Nair, Camilla Wattrus, Saiqa Mullick, Melanie Pleaner, Elzette Rousseau, Hasina Subedar, Dvora Joseph-Davey, Johan Hugo, Sinead Delany-Moretlwe, Linda-Gail Bekker   +10 more
doaj   +2 more sources

Impact of Tenofovir Alafenamide Sub‐Dermal Implant Insertion Site Scarring on Acceptability and HIV Prevention Preferences: A Prospective Cohort Study in Durban, South Africa [PDF]

Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.
ABSTRACT Introduction The CAPRISA 018 Phase I trial evaluated the safety, tolerability and pharmacokinetics of a 110 mg tenofovir alafenamide (TAF) implant for HIV prevention in South African women. This follow‐up cohort study, CAPRISA 097, assessed the long‐term resolution of implant site reactions (ISRs) after implant removal and explored user ...
Tanuja N. Gengiah, Lara Lewis, Ishana Harkoo, Nqobile Myeni, Leila E. Mansoor, Salim S. Abdool Karim, Quarraisha Abdool Karim   +6 more
wiley   +2 more sources

Transforming PrEP marketing: understanding the place of PrEP in the hearts and minds of adolescent girls and young women in sub‐Saharan Africa [PDF]

Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Abstract Introduction Adolescent girls and young women (AGYW) in sub‐Saharan Africa (SSA) remain one of the populations most affected by HIV. As HIV prevention options expand—such as the introduction of the dapivirine ring, long‐acting injectable cabotegravir and other potential long‐acting methods—alongside oral pre‐exposure prophylaxis (PrEP), AGYW ...
Emily de Lacy Donaldson, Elmari Briedenhann, Patriciah Jeckonia, Casey Bishopp, Anelde Greeff, Definate Nhamo   +5 more
wiley   +2 more sources