Results 141 to 150 of about 2,007,940 (182)

U.S. Women Need the Dapivirine Ring, Too: FDA as Structural Barrier to HIV Prevention for Women

AIDS Education and Prevention, 2022
The dapivirine monthly vaginal ring-a discreet, anti-HIV microbicide created specifically for women-has received a positive scientific opinion by the European Medicines Agency and is included in the WHO HIV prevention guidelines.
Erica Gollub
exaly   +2 more sources

Correlates of Adherence to the Dapivirine Vaginal Ring for HIV-1 Prevention

AIDS and Behavior, 2021
Understanding characteristics associated with adherence to pre-exposure prophylaxis (PrEP) methods for HIV-1 prevention may assist with optimizing implementation efforts. The dapivirine vaginal ring is a novel topical PrEP delivery method. Using data from a randomized, double-blind, placebo-controlled, phase III trial of the dapivirine vaginal ring ...
Jared M Baeten   +2 more
exaly   +3 more sources

The Influence of Perceived Dapivirine Vaginal Ring Effectiveness on Social Disclosure and Ring Adherence

AIDS and Behavior, 2021
We analyzed data from 1428 users of the dapivirine vaginal ring, who participated in the MTN-020/ASPIRE phase III trial and subsequent open-label extension MTN-025/HOPE trial, to examine relationships between perceived ring protection, social disclosures, and self-reported ring adherence. In HOPE, 77% perceived the ring to be highly effective, and this
Ariane van der Straten   +2 more
exaly   +3 more sources

Development of dapivirine vaginal ring for HIV prevention

Antiviral Research, 2013
In the continuing effort to develop effective HIV prevention methods for women, a vaginal ring containing the non-nucleoside reverse transcriptase inhibitor dapivirine is currently being tested in two safety and efficacy trials. This paper reviews dapivirine ring's pipeline development process, including efforts to determine safe and effective dosing ...
Jeremy Nuttall   +2 more
exaly   +3 more sources

Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring

open access: yesAIDS Research and Human Retroviruses, 2009
Vaginal delivery of 200 mg or 25 mg dapivirine from intravaginal rings (IVRs) was evaluated over a 7-day period in two phase 1 safety trials (IPM001 and IPM008, respectively) in a total of 25 healthy women 19 to 46 years of age. The IVR was generally safe and well tolerated with similar adverse events observed in the placebo and dapivirine groups ...
Romano, J.   +10 more
openaire   +4 more sources

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