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Acceptability and Use of Digital Health and Artificial Intelligence-Enabled Chatbots for Sexual and Reproductive Health Among Lesbian, Bisexual, and Queer Women of Color in the United States: Cross-Sectional Survey Study.

J Med Internet Res
Threats M, Gray M.
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Development of dapivirine vaginal ring for HIV prevention

Antiviral Research, 2013
In the continuing effort to develop effective HIV prevention methods for women, a vaginal ring containing the non-nucleoside reverse transcriptase inhibitor dapivirine is currently being tested in two safety and efficacy trials. This paper reviews dapivirine ring's pipeline development process, including efforts to determine safe and effective dosing ...
Bríd, Devlin, Jeremy, Nuttall, Susan, Wilder, Cynthia, Woodsong, Zeda, Rosenberg   +4 more
openaire   +4 more sources

Correlates of Adherence to the Dapivirine Vaginal Ring for HIV-1 Prevention

AIDS and Behavior, 2021
Understanding characteristics associated with adherence to pre-exposure prophylaxis (PrEP) methods for HIV-1 prevention may assist with optimizing implementation efforts. The dapivirine vaginal ring is a novel topical PrEP delivery method. Using data from a randomized, double-blind, placebo-controlled, phase III trial of the dapivirine vaginal ring ...
Marla J. Husnik, Elizabeth R. Brown, Sufia S. Dadabhai, Zakir Gaffoor, Nitesha Jeenarain, Flavia Matovu Kiweewa, Edward Livant, Leila E. Mansoor, Brenda Gati Mirembe, Thesla Palanee-Phillips, Devika Singh, Samantha Siva, Lydia Soto-Torres, Ariane van der Straten, Jared M. Baeten, Jared Baeten, Thesla Palanee-Phillips, Elizabeth Brown, Lydia Soto-Torres, Katie Schwartz, Bonus Makanani, Francis Martinson, Linda-Gail Bekker, Vaneshree Govender, Samantha Siva, Zakir Gaffoor, Logashvari Naidoo, Arendevi Pather, Nitesha Jeenarain, Felix Mhlanga   +29 more
openaire   +4 more sources

Dapivirine Vaginal Ring for HIV-1 Prevention

New England Journal of Medicine, 2017
Jared M, Baeten, Elizabeth R, Brown, Sharon L, Hillier   +2 more
openaire   +6 more sources

The Influence of Perceived Dapivirine Vaginal Ring Effectiveness on Social Disclosure and Ring Adherence

AIDS and Behavior, 2021
We analyzed data from 1428 users of the dapivirine vaginal ring, who participated in the MTN-020/ASPIRE phase III trial and subsequent open-label extension MTN-025/HOPE trial, to examine relationships between perceived ring protection, social disclosures, and self-reported ring adherence. In HOPE, 77% perceived the ring to be highly effective, and this
Marie C. D. Stoner, Elizabeth R. Brown, Thesla Palanee-Phillips, Leila E. Mansoor, Tchangani Tembo, Gonasagrie Nair, Carolyne Akello, Linly Seyama, Nitesha Jeenarain, Logashvari Naidoo, Nyaradzo Mgodi, Portia Hunidzarira, Miria Chitukuta, Ariane van der Straten, Jared Baeten, Thesla Palanee-Phillips, Nyaradzo Mgodi, Elizabeth Brown, Lydia Soto-Torres, Katie Schwartz, Ashley Mayo, Bonus Makanani, Francis Martinson, Lameck Chinula, Linda-Gail Bekker, Gonasagrie Nair, Vaneshree Govender, Samantha Siva, Zakir Gaffoor, Logashvari Naidoo, Arendevi Pather, Nitesha Jeenarain, Gita Ramjee, Dishiki Kalonji, Nishanta Singh, Leila Mansoor, Flavia Matovu, Brenda Gati, Portia Hunidzarira, Felix Mhlanga   +39 more
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Women’s motivations for participating in the dapivirine vaginal ring open label extension study

AIDS Care, 2023
Open-Label Extension (OLE) studies are important in the drug development process and are used to further support the licensing applications and regulatory approvals of products. We aimed to understand why women chose to join the HOPE OLE study - where women were offered the dapivirine vaginal ring after two pivotal trials were completed - through data ...
Kalendri Naidoo, Elizabeth T. Montgomery, Ariana W. K. Katz, Morgan Garcia, Sarita Naidoo, Leila E. Mansoor   +5 more
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