Results 161 to 170 of about 2,007,940 (182)

Depression Among Pregnant and Breastfeeding Persons Participating in Two Randomized Trials of the Dapivirine Vaginal Ring and Oral Pre-Exposure Prophylaxis (PrEP) in Malawi, South Africa, Uganda, and Zimbabwe

Aids and Behavior
Depression is associated with lower adherence to oral pre-exposure prophylaxis (PrEP) to prevent HIV, but data are not currently available on how depression may affect use of other HIV prevention methods including the dapivirine vaginal ring (DVR).
Marie C. D. Stoner, Florence Mathebula, Natasha Sedze, L. Seyama, Rebone Mohuba, Zayithwa Fabiano, J. Etima, Alinda M. Young, Rachel Scheckter, A. van der Straten, Jeanna M. Piper, L. Noguchi, Elizabeth T. Montgomery, Iván C. Balán   +13 more
semanticscholar   +1 more source

A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women

AIDS, 2014
Women-initiated HIV-prevention products are urgently needed. To address this need, a trial was conducted to assess the safety and pharmacokinetics of a silicone elastomer matrix vaginal ring containing 25 mg of the antiretroviral drug dapivirine when used continuously for 28 consecutive days.A double-blind, randomized, placebo-controlled trial was ...
Annalene, Nel, Wouter, Haazen, Jeremy, Nuttall, Joseph, Romano, Zeda, Rosenberg, Neliëtte, van Niekerk   +5 more
openaire   +2 more sources

Understanding the sources of efficacy dilution in a trial of a monthly dapivirine vaginal ring for HIV-1 prevention

International Journal of STD and AIDS
Introduction Women-initiated HIV – 1 prevention products are key to reducing women’s HIV-1 risk. Clinical trials of vaginal microbicides have shown limited to no efficacy in intention-to-treat (ITT) analyses.
K. Peebles, L. Matrajt, J. Baeten, T. Palanee-Phillips, Elizabeth R. Brown   +4 more
semanticscholar   +1 more source

Dapivirine Vaginal Ring for HIV-1 Prevention

New England Journal of Medicine, 2017
Jared M, Baeten, Elizabeth R, Brown, Sharon L, Hillier   +2 more
openaire   +4 more sources

A Combination Vaginal Ring Releasing Dapivirine and Darunavir

AIDS Research and Human Retroviruses, 2014
Karl Malcolm, Diarmaid Murphy, Delphine Desjardins, Nathalie Dereuddre-Bosquet, Patricia Brochard, Ludivine Perrot, Alain Pruvost, Roger Le Grand, Ole Lagatie, Leen Vanhooren, Maxim Feyaerts, Jens Van Roey   +11 more
openaire   +1 more source

Safety of dapivirine vaginal rings during breastfeeding

The Lancet HIV
Katrina F, Ortblad, Kenneth, Ngure
openaire   +2 more sources

Comparison of dissolution testing methods for the 25 mg dapivirine vaginal ring

2018
Background: Dissolution testing of the 25 mg dapivirine (DPV) vaginal ring has historically relied on a non-compendial shaking incubator method. Typically, individual rings in a sealed glass flask containing a defined volume of release medium are placed in a temperature-controlled shaking incubator.
Malcolm, Robert; id_orcid 0000-0002-1276-7095, McCoy, Clare; id_orcid 0000-0002-1428-4046, Murphy, Diarmaid, Boyd, Peter, Derrick, Tiffany, Spence, Patrick, Devlin, Brid   +6 more
openaire   +1 more source

Dapivirine ring reduces HIV acquisition

Nature Reviews Urology, 2016
openaire   +1 more source

Using Emoji Stickers to Understand End-User Opinions of the Dapivirine Vaginal Ring for HIV Prevention

AIDS and Behavior, 2021
Ariana Katz, Elizabeth T Montgomery, Leila E Mansoor   +2 more
exaly  

Correlates of Dapivirine Vaginal Ring Acceptance among Women Participating in an Open Label Extension Trial

AIDS and Behavior, 2022
Brenda Mirembe, Sufia Dadabhai, Elizabeth R Brown   +2 more
exaly