Results 21 to 30 of about 11,723 (189)

A case report of Dapsone Hypersensitivity Syndrome in a Child with Lepromatous Leprosy and Potential Genetic Element

Sri Lanka Journal of Medicine, 2022
Dapsone hypersensitivity syndrome (DHS) is characterized by fever, skin rash, eosinophilia, lymphadenopathy, and multi systemic manifestations following Dapsone therapy [1].
S. P. N. Weerasekara, C. Abeynayake, S. Abeywardana, J. Akarawita, N. Senadheera   +4 more
doaj   +1 more source

Type 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report. [PDF]

Respirol Case Rep
We report a case of a man developing erythema nodosum leprosum after initiating treatment for drug‐susceptible pulmonary tuberculosis. This highlights the importance of recognising concomitant leprosy in patients with tuberculosis since these mycobacterial infections require different long‐term multidrug regimens.
Villanueva CAG, Ortiz YRH, Mojica WP, Albay AB.   +3 more
europepmc   +2 more sources

Dapsone – mechanism of action, safety of use and the role in the treatment of bullous pemphigoid according to current recommendations

Przegląd Dermatologiczny, 2016
Dapsone has been used in the treatment of bullous pemphigoid (BP) for over 50 years. According to the 2015 European Recommendations, the treatment of choice in BP are potent topical corticosteroids. In this article, we present data from the literature on
Magdalena Żychowska, Aleksandra Batycka-Baran, Jacek Szepietowski, Wojciech Baran   +3 more
doaj   +1 more source

Multiple docking analysis and In silico absorption, distribution, metabolism, excretion, and toxicity screening of anti-leprosy phytochemicals and dapsone against dihydropteroate synthase of Mycobacterium leprae

International Journal of Mycobacteriology, 2019
Background: Leprosy is a neglected tropical disease affecting millions of people. The current treatment against leprosy includes various antibacterial drugs of which dapsone is known to bind to dihydropteroate synthase of Mycobacterium leprae. Dapsone is
Sumit T Halder, Tehseen M Dhorajiwala, Lalit R Samant,   +3 more
doaj   +1 more source

Dapsone syndrome with acute renal failure during leprosy treatment: case report

Brazilian Journal of Infectious Diseases
Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection.
Edson Nogueira Alves-Rodrigues, Luciano Correa Ribeiro, Margareth Dióz Silva, Arley Takiuchi, Cor Jesus Fernandes Fontes   +4 more
doaj   +1 more source

Dapsone [PDF]

Reactions Weekly, 2021
  +5 more sources

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, EarlyView.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Use of dapsone in chronic/refractory immune thrombocytopenic patients: A single center experience

Turkish Journal of Internal Medicine, 2023
Background: Dapsone is a second-line therapy for immune thrombocytopenia (ITP). It is cost-effective, with a response rate comparable to other drugs used as second-line therapy, such as azathioprine, danazol, cyclophosphamide, cyclosporine, vincristine ...
Ömer Candar, Vildan Ozkocaman, Tuba Ersal, Tuğçe Zor Turna, İbrahim Ethem Pınar, Cumali Yalçın, Bedrettin Orhan, Sinem Çubukçu, Tuba Güllü Koca, Rıdvan Ali, Fahir Özkalemkaş   +10 more
doaj   +1 more source

Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts

European Journal of Organic Chemistry, EarlyView.
A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha, Gabriel G. Rocha, Fábio M. F. Santos, Stefan Bräse, M. Manuel B. Marques   +4 more
wiley   +1 more source