Results 21 to 30 of about 15,491 (225)

Dapsone – mechanism of action, safety of use and the role in the treatment of bullous pemphigoid according to current recommendations

Przegląd Dermatologiczny, 2016
Dapsone has been used in the treatment of bullous pemphigoid (BP) for over 50 years. According to the 2015 European Recommendations, the treatment of choice in BP are potent topical corticosteroids. In this article, we present data from the literature on
Magdalena Żychowska, Aleksandra Batycka-Baran, Jacek Szepietowski, Wojciech Baran   +3 more
doaj   +1 more source

Multiple docking analysis and In silico absorption, distribution, metabolism, excretion, and toxicity screening of anti-leprosy phytochemicals and dapsone against dihydropteroate synthase of Mycobacterium leprae

International Journal of Mycobacteriology, 2019
Background: Leprosy is a neglected tropical disease affecting millions of people. The current treatment against leprosy includes various antibacterial drugs of which dapsone is known to bind to dihydropteroate synthase of Mycobacterium leprae. Dapsone is
Sumit T Halder, Tehseen M Dhorajiwala, Lalit R Samant,   +3 more
doaj   +1 more source

Clinical outcomes of adverse cardiovascular events in patients with acute dapsone poisoning [PDF]

Clinical and Experimental Emergency Medicine, 2016
Objective Adverse cardiovascular events (ACVEs) account for a large proportion of the morbidities and mortalities associated with drug overdose emergencies. However, there are no published reports regarding outcomes of ACVEs associated with acute dapsone
Kyung Sik Kang, Hyung Il Kim, Oh Hyun Kim, Kyoung Chul Cha, Hyun Kim, Kang Hyun Lee, Sung Oh Hwang, Yong Sung Cha   +7 more
doaj   +1 more source

Dapsone syndrome with acute renal failure during leprosy treatment: case report

Brazilian Journal of Infectious Diseases
Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection.
Edson Nogueira Alves-Rodrigues, Luciano Correa Ribeiro, Margareth Dióz Silva, Arley Takiuchi, Cor Jesus Fernandes Fontes   +4 more
doaj   +1 more source

Dapsone [PDF]

Reactions Weekly, 2021
  +5 more sources

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Myocarditis in dapsone-induced drug reaction with eosinophilia and systemic symptoms—a case report and review of the literature

Dermatologica Sinica, 2011
Dapsone (4,4′-diaminodiphenylsulfone) has been used for a variety of dermatological conditions. Dapsone-induced drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but severe drug reaction characterized by fever, cutaneous eruption ...
Wei-Hsuan Li, Han-Nan Liu, Ding-Dar Lee
doaj   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro

Molecules
Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood.
Sara Rakočević, Vanja Mališ, Ljiljana Kozić, Anđela Dubovina, Marija Drakul, Dejan Bokonjić, Miodrag Čolić, Dušan Mihajlović   +7 more
doaj   +1 more source