Results 1 to 10 of about 4,315 (233)
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease [PDF]
JCI Insight, 2023 Mutation of the ATP2A2 gene encoding sarco-endoplasmic reticulum calcium ATPase 2 (SERCA2) was linked to Darier disease more than 2 decades ago; however, there remain no targeted therapies for this disorder causing recurrent skin blistering and ...
Shivam A. Zaver +7 more
doaj +4 more sources
Darier Disease – A Multi-organ Condition? [PDF]
Acta Dermato-Venereologica, 2021 Darier disease is a severe, rare autosomal dominant inherited skin condition caused by mutations in the ATP2A2 gene encoding sarcoendoplasmic reticulum Ca2+-ATPase isoform 2 in the endoplasmic reticulum.
Etty Bachar-Wikström +1 more
exaly +3 more sources
Diagnosis and management of vulvar Darier disease: A case report [PDF]
Case Reports in Women's Health, 2023 Darier disease is an autosomal dominant disorder with hyperkeratotic papules affecting primarily seborrheic areas of the upper chest, back, forehead, scalp, nasolabial folds, ears, and, less frequently, the oral mucosa.
Ipek Evruke +3 more
doaj +3 more sources
Dermatology Online Journal, 2016 We present a 58-year-old woman with bipolardisorder and with a longstanding history of yellowbrown,hyperkeratotic papules in a seborrheicdistribution and nail changes. Her father andpaternal grandmother had similar eruptions and alsohad psychiatric disease. Histopathologic examinationshowed acantholysis and dyskeratosis, which wasconsistent with Darier-
Christman, Mitalee P +5 more
openaire +5 more sources
Darier Disease with Psoriasis [PDF]
Medicina, 2022 Darier disease is an autosomal dominant disorder with dark crusty patches and is classified as hereditary acantholytic dermatosis. Keratotic papules and crust are often present on the scalp, forehead, chest, back, upper arms, elbows, groin, and behind ...
Seok-Young Kang +6 more
doaj +2 more sources
Darier-White disease and Psychiatric disorders: A Case Report [PDF]
European Psychiatry, 2022 Introduction Darier-White disease (DD) is a rare genodermatosis of dominant autosomic inheritance characterized by the keratinization of epidermis, nails and mucous membrane.
R.L. Esteve +3 more
doaj +2 more sources
Nepal Journal of Dermatology, Venereology & Leprology, 2012 Darier’s disease was described inependently by Darier and White in 1989 AD. Reported prevalence varies from 1/100,000 in Denmark to 1 in 30- 35,000 in northern England and Scotland.1 Darier’s disease has been reported from other parts of the world ...
A Amatya +5 more
doaj +5 more sources
Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
Interdisciplinary Neurosurgery, 2021 Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis.
Mohamad Syafeeq Faeez Md Noh +5 more
doaj +2 more sources
Darier disease: the use of dermoscopy in monitoring acitretin treatment [PDF]
Anais Brasileiros de Dermatologia, 2022 Darier disease is an uncommon autosomal dominant inherited disease, caused by a mutation in the ATP2A2 gene. The clinical findings are hyperkeratotic papules on the trunk, scalp, face, and neck, maceration of intertriginous areas, palmar pits, whitish ...
Catalina Silva-Hirschberg +3 more
doaj +2 more sources
Carbon dioxide laser treatment for Darier disease [PDF]
JAAD InternationalHasina Maredia, MD +3 more
doaj +3 more sources