Results 101 to 110 of about 2,442,143 (290)

Dark current at TTFL rf-gun

, 2000
22nd International Free Electron Laser Conference and 7th FEL Users Workshop, Durham, United States, 13 Aug 2000 - 18 Aug 2000; 2 pp. (2000).
Sertore, D., Schreiber, S., Zapfe, K., Huber, D., Michelato, P.   +4 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Influence of Boron Diffusion on Photovoltaic Parameters of n+-p-p+ Silicone Structures and Based Photodetectors

East European Journal of Physics
The paper investigates the photovoltaic properties of the silicon n+-p-p+-structures and photodiodes made on their basis. It was found that boron diffusion to the reverse side of the substrate, in addition to creating an ohmic contact, generates ...
Mykola S. Kukurudziak, Eduard V. Maistruk, Ivan P. Koziarskyi   +2 more
doaj   +1 more source

Compensation for Process and Temperature Dependency in a CMOS Image Sensor

Sensors, 2019
This paper analyzes and compensates for process and temperature dependency among a (Complementary Metal Oxide Semiconductor) CMOS image sensor (CIS) array. Both the analysis and compensation are supported with experimental results on the CIS’s dark
Shuang Xie, Albert Theuwissen
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Heat engineering characteristics of the radiator for effective electronic equipment cooling systems

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2011
The article presents the results of heat transfer charac-teristics research of the radiator on basis of a heat pipe for cooling of personal computer elements. It is determined that using acetone and ethanol as heat carriers under heat flow density q4·104
Rudenko A. I., Kravetz V. Yu., Zaripov V. K.   +2 more
doaj  

Charge-Domain Type 2.2 µm BSI Global Shutter Pixel with Dual-Depth DTI Produced by Thick-Film Epitaxial Process

Sensors
We developed a 2.2 µm backside-illuminated (BSI) global shutter (GS) pixel featuring true charge-domain-correlated double sampling (CDS). To enhance the inverse parasitic light sensitivity (1/PLS), we implemented a thick-film epitaxial process ...
Toshifumi Yokoyama, Masafumi Tsutsui, Yoshiaki Nishi, Yoshihiro Noguchi, Masahiko Takeuchi, Masahiro Oda, Fenigstein Amos   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Passivation of MWIR Heterostructure p-InAsSbP/n-InAs Photodiodes Using SiO₂ Layers for Near-Room-Temperature Operation

Proceedings
We examined the effect of SiO2 passivation on the parameters of mesa heterostructure InAs/InAsSbP photodiodes with a spectral responsivity 50% cut off at 3.5 µm at 295 K, specific to the InAs absorber layer.
Jarosław Pawluczyk, Krzysztof Kłos, Oskar Ślęzak, Kinga Majkowycz, Krzysztof Murawski, Tetiana Manyk, Jarosław Rutkowski, Piotr Martyniuk   +7 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source