Results 61 to 70 of about 8,495,694 (247)

2D/3D Perovskite Surface Passivation-Enabled High-Detectivity Near-Infrared Photodiodes

open access: yesSensors
Due to high responsivity and wide spectral sensitivity, metal halide perovskite photodiodes have a wide range of applications in the fields of visible light and near-infrared photodetection.
Xuefeng Huangfu   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The clustering of dark matter, haloes & galaxies [PDF]

open access: yes, 2008
In this thesis I study the spatial distribution of galaxies, haloes and dark matter particles using a suite of state-of-art cosmological N-body simulations of the growth structure in the Universe.
Angulo de la Fuente, Raúl Esteban
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Influence of displacement damage dose on dark current distributions of irradiated CMOS image sensors [PDF]

open access: yes
Dark current increase distributions due to displacement damages are modeled using displacement damage dose concept. Several CMOS image sensors have been exposed to neutrons or protons and we have characterized their degradation in terms of dark current ...
Goiffon, Vincent   +7 more
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

The Clustering of Dark Matter, Haloes & Galaxies [PDF]

open access: yes, 2008
In this thesis I study the spatial distribution of galaxies, haloes and dark matter particlesin the Universe. The subjects investigated are conceptually divided into three areas.One line of research, which is made up of Chapters 2 and 3, is to explore ...
Raúl Esteban Angulo de la Puente,
core  

Characterization of a Field Spectroradiometer for Unattended Vegetation Monitoring. Key Sensor Models and Impacts on Reflectance

open access: yesSensors, 2015
Field spectroradiometers integrated in automated systems at Eddy Covariance (EC) sites are a powerful tool for monitoring and upscaling vegetation physiology and carbon and water fluxes.
Javier Pacheco-Labrador   +1 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Dark aeolian sediments in Martian craters: Composition and sources [PDF]

open access: yes, 2011
Our research focuses on the mineralogical characteristics of dark sediment deposits in Martian craters (dunes, dune fields, and sand sheets) and their local sediment sources, carried out on the basis of 70 selected localities.
R. Jaumann   +7 more
core   +1 more source

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