Results 81 to 90 of about 1,123,493 (287)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Thermodynamics of dark energy [PDF]
Fortschritte der Physik, 2008 AbstractThermodynamic properties of dark energy are discussed assuming that dark energy is described in terms of a selfinteracting complex scalar. We first show that, under certain assumptions, selfinteracting complex scalar field theories are equivalent to purely kinetic k‐essence models.
openaire +3 more sources
ON ANISOTROPIC DARK ENERGY [PDF]
Modern Physics Letters A, 2009 Since the discovery of accelerated expansion of the universe, it was necessary to introduce a new component of matter distribution called dark energy. The standard cosmological model considers isotropy of the pressure and assumes an equation of state p = ωρ, relating the pressure p and the energy density ρ.
M. F. A. da Silva +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Dark Energy: The Shadowy Reflection of Dark Matter?
Entropy, 2016 In this article, we review a series of recent theoretical results regarding a conventional approach to the dark energy (DE) concept. This approach is distinguished among others for its simplicity and its physical relevance.
Kostas Kleidis, Nikolaos K. Spyrou
doaj +1 more source
Classical and Quantum Gravity, 2015 We study the classical dynamics of a non-abelian Higgs theory coupled to gravity in an isotropic and homogeneous Universe. For non-minimal coupling, this theory leads to a model of cosmic inflation that is very attractive due to its simplicity and consistency with the latest experimental data.
openaire +4 more sources
RECONSTRUCTING DARK ENERGY [PDF]
International Journal of Modern Physics D, 2006 This review summarizes recent attempts to reconstruct the expansion history of the universe and to probe the nature of dark energy. Reconstruction methods can be broadly classified into parametric and non-parametric approaches. It is encouraging that, even with the limited observational data currently available, different approaches give consistent ...
Alexei A. Starobinsky, Varun Sahni
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Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley +1 more source
Dark Energy - Dark Matter Unification: Generalized Chaplygin Gas Model [PDF]
, 2005 We review the main features of the generalized Chaplygin gas (GCG) proposal for unification of dark energy and dark matter and discuss how it admits an unique decomposition into dark energy and dark matter components once phantom-like dark energy is excluded.
arxiv +1 more source