Results 101 to 110 of about 242,972 (318)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Dark energy and Dark matter

open access: yes
This paper investigates the dynamic interplay between dark energy and dark matter using an optimized energy cycle framework. Observational data from the Planck mission’s cosmic microwave background (CMB) measurements at frequencies such as 30 GHz and 100 GHz are integrated into the model to validate predictions.
openaire   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Formation of galaxies and large-scale structure with cold dark matter [PDF]

open access: green, 1984
George R. Blumenthal   +3 more
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Limits on cold dark matter candidates from an ultralow background germanium spectrometer [PDF]

open access: green, 1987
S. P. Ahlen   +5 more
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Source Count Distribution of Fermi LAT Gamma-Ray Blazars Using Novel Nonparametric Methods

open access: yesUniverse
We utilized a sample from the Fermi-LAT 14-year Source Catalog by adjusting the flux detection threshold, enabling us to derive the intrinsic source count distribution dN/dF25 of extragalactic blazars using nonparametric, unbinned methods developed by ...
Xuhang Yin, Houdun Zeng
doaj   +1 more source

Rates for inelastic nuclear excitation by dark matter particles [PDF]

open access: green, 1988
John Ellis   +2 more
openalex   +1 more source

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