Results 101 to 110 of about 1,660,126 (341)
, 2015 In single-component theories of dark matter, the $2\to 2$ amplitudes for dark-matter production, annihilation, and scattering can be related to each other through various crossing symmetries.
Dienes, Keith R. +3 more
core +1 more source
Primordial Black Holes and a Common Origin of Baryons and Dark Matter [PDF]
, 2021 J. García-Bellido +2 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Hidden Hot Dark Matter as Cold Dark Matter [PDF]
, 2009 We show that hidden hot dark matter, hidden-sector dark matter with interactions that decouple when it is relativistic, is a viable dark matter candidate provided it has never been in thermal equilibrium with the particles of the standard model.
Sigurdson, Kris
core +1 more source
Signatures of Self-Interacting Dark Matter in the Matter Power Spectrum and the CMB
, 2018 We consider a self-interacting dark matter model in which the massive dark photon mediating the self-interaction decays to light dark fermions to avoid over-closing the universe.
Huo, Ran +3 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Light spin-1/2 or spin-0 Dark Matter particles
, 2004 We recall and precise how light spin-0 particles could be acceptable Dark Matter candidates, and extend this analysis to spin-1/2 particles. We evaluate the (rather large) annihilation cross sections required, and show how they may be induced by a new ...
B. Lee +26 more
core +2 more sources
Physics Letters B, 2003 Velocity-dependent interactions in a fundamental-string dominated universe lead quite naturally, with reasonable assumptions on initial conditions, to an accelerating expanding universe without assuming the existence of a cosmological constant. This result also holds generically for a universe dominated by moving extremal black holes, owing to a ...
openaire +2 more sources
Soliton Random Walk and the Cluster-Stripping Problem in Ultralight Dark Matter [PDF]
, 2020 Hsi-Yu Schive +2 more
openalex +1 more source