Results 131 to 140 of about 4,072,824 (320)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

The inflaton as dark matter [PDF]

open access: yesThe European Physical Journal C, 1998
17 pages, 4 eps-figures. To be published in Zeitschr. fuer Physik C.
Georg Kreyerhoff, Saul Barshay
openaire   +4 more sources

Unexpected major geomagnetic storm caused by faint eruption of a solar trans-equatorial flux rope

open access: yesNature Communications
Some geomagnetic storms’ solar origins are ambiguous, making them hard to predict. On March 23, 2023, a severe geomagnetic storm occurred, however, forecasts based on remote-sensing observations failed to predict it.
Weilin Teng   +3 more
doaj   +1 more source

The ScotoSinglet Model: a scalar singlet extension of the Scotogenic Model

open access: yesJournal of High Energy Physics, 2021
The Scotogenic Model is one of the most minimal models to account for both neutrino masses and dark matter (DM). In this model, neutrino masses are generated at the one-loop level, and in principle, both the lightest fermion singlet and the lightest ...
Ankit Beniwal   +4 more
doaj   +1 more source

A galaxy lacking dark matter [PDF]

open access: yesNature, 2018
Studies of galaxy surveys in the context of the cold dark matter paradigm have shown that the mass of the dark matter halo and the total stellar mass are coupled through a function that varies smoothly with mass.
P. V. Dokkum   +11 more
semanticscholar   +1 more source

Dark Matter and Dark Energy

open access: yes, 2004
I briefly review our current understanding of dark matter and dark energy. The first part of this paper focusses on issues pertaining to dark matter including observational evidence for its existence, current constraints and the `abundance of ...
197   +13 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Classification of three-family flavoured DFSZ axion models that have no domain wall problem

open access: yesJournal of High Energy Physics
We provide an exhaustive classification of three-family DFSZ axion models that have no cosmological domain wall problem. This result is obtained by making the Peccei-Quinn symmetry flavour dependent in certain specific ways, thus reinforcing a possible ...
Peter Cox   +4 more
doaj   +1 more source

Warm dark matter chills out: constraints on the halo mass function and the free-streaming length of dark matter with eight quadruple-image strong gravitational lenses [PDF]

open access: yesMonthly notices of the Royal Astronomical Society, 2019
The free-streaming length of dark matter depends on fundamental dark matter physics, and determines the abundance and concentration of dark matter haloes on sub-galactic scales.
D. Gilman   +5 more
semanticscholar   +1 more source

Dark Matter in the Coming Decade: Complementary Paths to Discovery and Beyond

open access: yes, 2015
In this report we summarize the many dark matter searches currently being pursued through four complementary approaches: direct detection, indirect detection, collider experiments, and astrophysical probes.
Bauer, Daniel   +18 more
core   +1 more source

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