Results 71 to 80 of about 4,316,616 (347)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Dark Matter Search in Missing Energy Events with NA64. [PDF]

open access: yesPhysical Review Letters, 2019
A search for sub-GeV dark matter production mediated by a new vector boson A^{'}, called a dark photon, is performed by the NA64 experiment in missing energy events from 100 GeV electron interactions in an active beam dump at the CERN SPS.
D. Banerjee   +50 more
semanticscholar   +1 more source

Dynamical Dark Matter: II. An Explicit Model

open access: yes, 2012
In a recent paper (arXiv:1106.4546), we introduced "dynamical dark matter," a new framework for dark-matter physics, and outlined its underlying theoretical principles and phenomenological possibilities.
A. G. Doroshkevich   +14 more
core   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Constraints on Light Dark Matter Particles Interacting with Electrons from DAMIC at SNOLAB. [PDF]

open access: yesPhysical Review Letters, 2019
We report direct-detection constraints on light dark matter particles interacting with electrons. The results are based on a method that exploits the extremely low levels of leakage current of the DAMIC detector at SNOLAB of 2-6×10^{-22}  A cm^{-2}.
A. Aguilar-Arevalo   +33 more
semanticscholar   +1 more source

Muonphilic dark matter explanation of gamma-ray galactic center excess: a comprehensive analysis

open access: yesJournal of High Energy Physics, 2022
The Galactic center gamma-ray excess (GCE) is a long-standing unsolved problem. One of candidate solutions, the dark matter (DM) annihilation, has been recently tested with other astrophysical observations, such as AMS-02 electron-positron spectra, Fermi
Murat Abdughani   +4 more
doaj   +1 more source

Dark matter from dark energy-baryonic matter couplings

open access: yes, 2011
We present a scenario in which a scalar field dark energy is coupled to the trace of the energy momentum tensor of the baryonic matter fields. In the slow-roll regime, this interaction could give rise to the cosmological features of dark matter.
Alejandro Avilés   +3 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Low-Mass Dark Matter Search with the DarkSide-50 Experiment. [PDF]

open access: yesPhysical Review Letters, 2018
We present the results of a search for dark matter weakly interacting massive particles (WIMPs) in the mass range below 20  GeV/c^{2} using a target of low-radioactivity argon with a 6786.0 kg d exposure.
P. Agnes   +193 more
semanticscholar   +1 more source

Constraining primordial black holes as dark matter using AMS-02 data

open access: yesEuropean Physical Journal C: Particles and Fields
Primordial black holes (PBHs) are the plausible candidates for the cosmological dark matter. Theoretically, PBHs with masses $$M_{\textrm{PBH}}$$ M PBH in the range of $$4\times 10^{14}\sim 10^{17}\,\textrm{g}$$ 4 × 10 14 ∼ 10 17 g can emit sub-GeV ...
Bing-Yu Su   +5 more
doaj   +1 more source

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