Results 41 to 50 of about 4,043,825 (280)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Nexus of the Dark Triad Personality Traits With Cyberbullying, Empathy, and Emotional Intelligence: A Structural-Equation Modeling Approach

open access: yesFrontiers in Psychology, 2021
This study set out to elucidate the complex suite of associations between the Dark Triad personality traits (Machiavellianism, narcissism, and psychopathy), emotional intelligence, empathy, and cyberbullying, as the respective findings regarding this ...
Estelle C. Schade   +2 more
doaj   +1 more source

Tales from the Dark Side: Privacy Dark Strategies and Privacy Dark Patterns [PDF]

open access: yesProceedings on Privacy Enhancing Technologies, 2016
Abstract Privacy strategies and privacy patterns are fundamental concepts of the privacy-by-design engineering approach. While they support a privacy-aware development process for IT systems, the concepts used by malicious, privacy-threatening parties are generally less understood and known.
Christoph Bösch 0001   +4 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Próby zdefiniowania pojęcia dark patterns w doktrynie i aktywności organów państw członkowskich Unii Europejskiej

open access: yesinternetowy Kwartalnik Antymonopolowy i Regulacyjny
Celem artykułu jest prześledzenie różnego sposobu definiowania pojęcia dark patterns w doktrynie oraz orzecznictwie organów działających na terytorium Unii Europejskiej, szczególnie z polskiej perspektywy.
Damian Kazimierski
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Mapping the Landscape of Dark Patterns Scholarship: A Systematic Literature Review [PDF]

open access: yes, 2023
peer reviewedDark patterns are increasingly ubiquitous in digital services and regulation, describing instances where designers use deceptive, manipulative, or coercive tactics to encourage end users to make decisions that are not in their best interest.
Ike Obi,   +3 more
core   +1 more source

Subscription model as a mechanism of digital stratification: precarity of access and cost of exit

open access: yesЦифровая социология
The article examines the subscription model (SaaS) as a socio-technical complex that produces new forms of digital inequality — ones that classical stratification theories, built around property, cannot account for.
U. B. Nomokonova, E. V. Artyushenkova
doaj   +1 more source

Towards Detecting Influential Members and Critical Topics from Dark Web Forums: A Data Mining Approach

open access: yesJournal of Information and Organizational Sciences, 2023
Conventionally, the Internet consists of three parts: Surface, Deep, and Dark Webs. In the last two decades, a massive increase in illicit activities took place on the different platforms of the Dark Web.
Faris Ali   +3 more
doaj   +1 more source

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