Results 51 to 60 of about 3,890,266 (282)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Shining a Light on Dark Patterns [PDF]

open access: yes, 2021
Dark patterns are user interfaces whose designers knowingly confuse users, make it difficult for users to express their actual preferences, or manipulate users into taking certain actions.
Luguri, Jamie   +2 more
core   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Cold and Thermal Neutron Single Grating Dark-Field Imaging Extended to an Inverse Pattern Regime

open access: yesApplied Sciences, 2022
Neutron dark-field imaging is a powerful tool for the spatially resolved characterization of microstructural features of materials and components. Recently, a novel achromatic technique based on a single absorption grating for the concurrent measurement ...
Matteo Busi   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A cautionary tale: children, dark patterns and normative perspectives

open access: yesOñati Socio-Legal Series
This article explores the intersection of dark patterns — deceptive design practices that manipulate user behavior—with children’s digital experiences, examining how universal cognitive vulnerabilities intersect with context-specific susceptibilities ...
Vitória Oliveira
doaj   +1 more source

Light dark matter showering under broken dark U(1) — revisited

open access: yesJournal of High Energy Physics, 2019
It was proposed recently that different chiralities of the dark matter (DM) fermion under a broken dark U(1) gauge group can lead to distinguishable signatures at the LHC through shower patterns, which may reveal the mass origin of the dark sector.
Junmou Chen   +4 more
doaj   +1 more source

Dark Patterns in the Interaction with Cookie Banners

open access: yesCoRR, 2021
5 pages, 3 figures, Position Paper at the Workshop "What Can CHI Do About Dark Patterns?" at the CHI Conference on Human Factors in Computing Systems (CHI 2021), May 8-13, 2021, Yokohama ...
Philip Hausner, Michael Gertz 0001
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Przeciwdziałanie praktykom dark patterns na przykładzie działań Prezesa Urzędu Ochrony Konkurencji i Konsumentów

open access: yesinternetowy Kwartalnik Antymonopolowy i Regulacyjny
Zakupy przez Internet stają się codziennością dla coraz większej grupy osób, a wiele aktywności przenosi się do sieci. Upowszechnienie możliwości załatwiania bieżących spraw online powoduje także podniesienie poziomu wiedzy o zachowaniach konsumentów na ...
Damian Kazimierski
doaj   +1 more source

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