Results 91 to 100 of about 332,113 (340)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

PCC-like induction of mitosis in Chara vulgaris antheridia initiating differentiation of spermatozoids in the darkness

open access: yesActa Societatis Botanicorum Poloniae, 2014
The objects of this research were the antheridial filament cells of Chara vulgaris which after 5-day mitodepressing treatment of the darkness reactivated mitosis (without light stimulation) in the result of the physiological state evocing the initiation ...
Maria Kwiatkowska
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Identification and Functional Characterization of Arabidopsis icl Mutant Under Trehalose Feeding in Light and Dark Conditions [PDF]

open access: yesJournal of Genetic Resources, 2019
Trehalose is a non-reducing sugar that plays an important role in plant growth and development. To study the role of trehalose on lipid metabolism and gluconeogenesis, Arabidopsis thaliana wild type (WT) and TreF (a line expressing trehalase) were grown ...
Aniseh Noroozipoor   +2 more
doaj   +1 more source

Properties of multi-partite dark states [PDF]

open access: yesarXiv, 2002
We investigate and define dark and semi-dark states for multiple qudit systems. For two-level systems, semi-dark and dark states are equivalent. We show that the semi-dark states are equivalent to the singlet states of the rotation group. They exist for many multiple qudit systems, whereas dark states are quite rare. We then show that when a dark state
arxiv  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Dark energy and dark matter haloes [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2005
16 p., 11 fig.; replaced with revised version, accepted for publication in MNRAS; corrected error (w=-1.5 halo mass function now agrees with Jenkins et al.
Andrew R. Zentner   +4 more
openaire   +3 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Sub-MeV Dark Sink Dark Matter [PDF]

open access: yesPhys. Rev. D 111 (2025) 3, 035027
A Dark Sink uses dark-sector interactions to siphon energy from dark matter to lighter dark degrees of freedom, i.e. dark radiation. Here, we extend dark matter models containing a Dark Sink to sub-MeV masses. We consider a Dark Sink model where the dark matter is charged under a light dark photon that has kinetic mixing with the Standard Model.
arxiv   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

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