Results 101 to 110 of about 18,687 (213)

HIV-1 Protease: Structural Perspectives on Drug Resistance

Viruses, 2009
Antiviral inhibitors of HIV-1 protease are a notable success of structure-based drug design and have dramatically improved AIDS therapy. Analysis of the structures and activities of drug resistant protease variants has revealed novel molecular mechanisms
Irene T. Weber, Johnson Agniswamy
doaj   +1 more source

Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]

, 2018
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core   +1 more source

Use of darunavir in HIV-infected women during pregnancy

Терапевтический архив, 2013
The use of antiretroviral drugs (ARVDs) in a mother and a child can reduce the risk of vertical transmission of human immunodeficiency virus (HIV) to less than 1%; therefore, highly active antiretroviral therapy is used in all pregnant women regardless ...
L Iu Afonina, E E Voronin
doaj  

Influence of Darunavir: β-cyclodextrin complex on the solubility of Darunavir

, 2016
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Kogawa, Ana Carolina, Corrêa, Josilene Chaves Ruela, Salgado, Hérida Regina Nunes   +2 more
openaire   +1 more source

Efficacy and tolerability of switching to a dual therapy with darunavir/ritonavir plus raltegravir in HIV-infected patients with HIV-1 RNA <= 50 cp/mL [PDF]

, 2017
Background: Nucleos(t)ide reverse transcriptase inhibitors (NRTI) toxicity may represent a threat for long-term success of combined antiretroviral therapy.
Antinori, A, Bonora, S, Carbone, A, Cozzi-Lepri, A, De Luca, A, Di Biagio, A, Di Giambenedetto, S, Gianotti, N, Madeddu, G, Rusconi, S   +9 more
core  

Prevalence of HIV-1 drug resistance in treated patients with viral load >50 copies/mL in 2009: a French nationwide study [PDF]

, 2017
Background Surveillance of HIV-1 drug resistance in treated patients with plasma viral load (VL) >50 copies/mL. Methods The protease and reverse transcriptase (RT) genes were systematically sequenced in samples from 756 patients with VL >50 copies/mL in ...
Assoumou, Lambert, Chaix, Marie-Laure, Costagliola, Dominique, Delaugerre, Constance, Descamps, Diane, Dos Santos, Georges, Izopet, Jacques, Marcelin, Anne-Geneviève, Masquelier, Bernard, Montes, Brigitte, Morand-Joubert, Laurence, Pakianather, Sophie, Plantier, Jean-Christophe, Ruffault, Annick, Wirden, Marc, Yerly, Sabine   +15 more
core  

Cobicistat/darunavir/cobicistat/darunavir/emtricitabine/tenofovir-alafenamide/darunavir/ritonavir [PDF]

Reactions Weekly, 2020
openaire   +1 more source

Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection

HIV/AIDS: Research and Palliative Care, 2016
Rustin D Crutchley,1 Rakesh C Guduru,2 Amy M Cheng1 1Department of Pharmacy Practice and Translational Research, College of Pharmacy, University of Houston, 2CompanionDX, Houston, TX, USA Abstract: Atazanavir/cobicistat (ATV/c) and darunavir/cobicistat (
Crutchley RD, Guduru RC, Cheng AM,
doaj  

Cardiovascular adverse events during treatment with darunavir-based regimens in an Italian observational study

Drug Design, Development and Therapy, 2019
A Antinori,1 S Rusconi,2 N Gianotti,3 T Bini,4 D Mancusi,5 R Termini51HIV/AIDS Department, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Rome, Italy; 2Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan,
Antinori A, Rusconi S, Gianotti N, Bini T, Mancusi D, Termini R   +5 more
doaj  

Formulation and characterization of solid lipid nanoparticles for an anti-retroviral drug darunavir [PDF]

, 2017

core   +1 more source