Results 81 to 90 of about 13,218 (206)
Chemical and Toxicological Analysis of Antiretroviral Drugs
Разработка и регистрация лекарственных средств, 2019 Introduction. Human Immunodeficiency Virus (HIV) is one of the main socially significant infection all over the world. HIV-positive patients take medical care, including antiretroviral drugs (ARVs) pharmacotherapy.T. N. Komarov, M. V. Belova, D. D. Stolyarova, I. E. Shohin, D. S. Bogdanova, O. A. Miskiv, Yu. V. Medvedev, I. M. Korenskaya +7 moredoaj +1 more sourceWeight and BMI Changes Following Initiation of Emtricitabine/Tenofovir Alafenamide Co-Formulated with Darunavir or Co-Administered with Dolutegravir in Overweight or Obese, ART-Naïve People Living with HIV-1
ClinicoEconomics and Outcomes Research, 2023 Prina Donga,1 Bruno Emond,2 Carmine Rossi,2 Brahim K Bookhart,1 Johnnie Lee,1 Gabrielle Caron-Lapointe,2 Fangzhou Wei,3 Marie-Hélène Lafeuille2 1Janssen Scientific Affairs, LLC, Titusville, NJ, USA; 2Analysis Group, Inc, Montréal, QC, Canada; 3Analysis ...Donga P, Emond B, Rossi C, Bookhart BK, Lee J, Caron-Lapointe G, Wei F, Lafeuille MH +7 moredoaj Decreased darunavir concentrations during once-daily co-administration with maraviroc and raltegravir: OPTIPRIM-ANRS 147 trial
, 2018 International audienceBackgroundThe OPTIPRIM-ANRS 147 trial compared intensive combination ART (darunavir/ritonavir, tenofovir disoproxil fumarate/emtricitabine, raltegravir and maraviroc) started early during primary HIV-1 infection with standard ...Ruquet, M, J M Molina, G Catalano, Simon, A, M Vassallo, S Ben Abdallah, M Parrinello, S Gallien, Naqvi, Alice, Pichon, F, Delfraissy, J, Makinson, A, C Arvieux, L Letranchant, F Fily, S Bonne, T Ferry, Amri, I, Reliquet, V, P Mathurin, M P Bouillon, Thierry, S, Veron, R, D Brosseau, T L'Yavanc, E Braun, Chauveau, M, M Shoai, C Allavena, Prevoteau Du Clary, F, C Katlama, Rami, A, de Lastours, V, D Lacoste, Morquin, D, C Baringhton, Antoine Cheret, Laurent Tran, Y Levy, E Ousseima, Augustin Normand, C, Joulié, A, Rehaiem, S, Laplantine, V, Senechal, A, Philippe Morlat, A Vallon, M Revest, Tassadit, T, Brosseau, D, F Balsarin, I Ravaux, Tourdjman, M, J J Jourdain, Bourdeaux, C, L Slama, F Clavel, H Leroy, Phung, B, A Rami, Pierre-François, S, V Thoirain, M A Valentin, Ponscarme, D, Obadia, M, Etienne, M, Cotte, L, Richier, L, Allavena, C, M Carrerre, Fauchere, V, A Durel, A Chéret, A Adda, J Pavie, Yeni, P, S Ferret, M Môle, Feuillebois, N, I Alcaraz, M Chauveau, Abel, S, Clavel, F, C M Ratajczak, Billaud, E, Hoen, B, P Abgueguen, J Goguel, F Raffi, Delaune, J, Lafeuillade, A, J F Dailloux, S Pierre-François, Môle, M, J Delgado, F Touam, F Brunel Dalmas, C Rioux, Chennebault, J, B Phung, F Borsa Lebas, E Fourn, Carrerre, M, N Viget, Corsini, N, Déborah Hirt, Stenzel, M, Debab, Y, May, T, Caldato, S, l'Yavanc, T, Vandenhende, M, J Lipman, V Reliquet, Cheret, Antoine, V Lambry, S Pailhes, Receveur, M, J Lippran, Raffi, F, A Therby, Lelievre, J, Katlama, C, Neau, D, Lacaze-Buzy, L, M Diemer, Brunet-François, C, V Lemoine, J Koffi, Véronique Avettand-Fenoel, Pressiat, Claire, Koffi, J, C Michaux, Kiorza, N, E Chakvetadze, M P Pietri, E Aissi, Ferry, T, C Goujard, Pialoux, G, Baringhton, C, F Caron, J M Jacquet, Durant, J, Louni, F, V Laplantine, H Hüe, Lascoux, C, N De Castro, Fialaire, P, F Pichon, Meyer, Laurence, Dailloux, J, N Bernard, Alice Naqvi, Rouzioux, Christine, Rioux, C, M Etienne, Loriette, M, W Rozenbaum, Huleux, T, J M Chennebault, Jacquet, J, Balkan, S, Merle, C, M C Receveur, C Brochier, Chapuzet, C, I Gueit, V Berrebi, Livrozet, J, Michaux, C, N Colin De Verdiere, Mathurin, P, Zheng, Yi, Briaud, A, Aissi, E, Shoai, M, C Tramoni, M Stenzel, C Burty, M Pauchard, Pavie, J, G Gras, P Chiarello, Diemer, M, Brochier, C, A Greder Belan, Atoui, N, C Lascoux, F Ajana, P Yeni, de la Tribonniere, X, A Makinson, Quertainmont, Y, Thoirain, V, J M Livrozet, X De La Tribonniere, N Feuillebois, Vassallo, M, M A Vandenhende, C Merle, F Louni, A Simon, D Makhloufi, Fily, F, Slama, L, S Wassoumbou, H Melliez, Allègre, T, F Prevoteau Du Clary, Fourn, E, V Fauchere, P Miailhes, Lascaux, A, I Schlienger, T Huleux, Giovanna, M, Miailhes, P, N Corsini, S Larrigue, A Senechal, Michelet, C, J Delaune, R Veron, Arvieux, C, F Paccalin, O Mounoury, Charlier, C, Balsarin, F, S Seang, A Naqvi, Rozenbaum, W, Lipman, J, S M Thierry, L Lacaze-Buzy, D Morquin, Ben Abdallah, S, Paccalin, F, D Salmon, Monnier, S, Vandamme, Y, null null, Dominguez, S, Schneider, L, L Schneider, Lafaurie, M, Catalano, G, G Pialoux, M Loriette, Valentin, M, B Bonnet, T Perpoint, A Chermak, Ousseima, E, Touam, F, Reynes, J, V Baclet, Bouchez, S, Ravaux, I, Gras, G, Leroy, H, Lippran, J, Biron, F, Dumont, C, Jourdain, J, P Fialaire, M Giovanna, El Alami Talbi, N, Hüe, H, B Marchou, J Durant, Lambry, V, V Garrait, Braun, E, Marchou, B, Poissy, J, Letranchant, L, J Reynes, P Dellamonica, Jean-Paul Viard, T Tassadit, Chidiac, C, S Monnier, I Amri, A Rachline, A Leplatois, Aslan, A, Gueit, I, Revest, M, Bonne, S, Yi Zheng, Hittinger, G, Scemla, A, Gallien, S, Alcaraz, I, Levy, Y, L Cuzin, P Morlat, Molina, J, Jeanblanc, F, Seang, S, Wassoumbou, S, C Chidiac, Berrebi, V, Chakvetadze, E, Goujard, C, C Michelet, Goguel, J, Melliez, H, Borsa Lebas, F, Viard, Jean-Paul, A Lafeuillade, F Biron, Laurence Meyer, V Rabier, A Boibieux, Lemoine, V, F Souala, Y M Vandamme, C Godard, A Briaud, Lacoste, D, Ratajczak, C, L Bernard, Pailhes, S, Hirt, Déborah, J Poissy, Brunel Dalmas, F, C Dumont, Rachline, A, Tramoni, C, Godard, C, Guiroy, F, Jean-Marc Treluyer, Souala, F, M Tourdjman, E Billaud, S Bouchez, Morlat, Philippe, Therby, A, Parrinello, M, Leplatois, A, M Varan, C Duvivier, Rabier, V, Ferret, S, Claire Pressiat, G Philip, N Atoui, Baclet, V, S Dominguez, Garrait, V, Viget, N, Duvivier, C, D Ponscarme, D Neau, Avettand-Fenoel, Véronique, Durel, A, Consigny, P, Delgado, J, V De Lastours, Chiarello, P, Tran, Laurent, Pauchard, M, Vallon, A, Morineau-Le-Houssine, P, Makhloufi, D, A Scemla, Larrigue, S, J F Delfraissy, J M Ragnaud, Perpoint, T, N Kiorza, L Richier, Treluyer, Jean-Marc, Ragnaud, J, Adda, A, Tattevin, P, T Allègre, Chapplain, J, Bouillon, M, Abgueguen, P, A Joulié, Varan, M, P Tattevin, J D Lelievre, C Charlier, S Caldato, Y Debab, M Lafaurie, Boibieux, A, B Hoen, S Rehaiem, P H Consigny, Schlienger, I, A Aslan, C Mededji, Colin de Verdiere, N, Cuzin, L, Dellamonica, P, C Bourdeaux, M Obadia, Burty, C, G Hittinger, Pietri, M, Ajana, F, Mededji, C, Greder Belan, A, S Balkan, J M Chapplain, Y Quertainmont, P Morineau-Le-Houssine, S Abel, T May, F Guiroy, Bernard, L, Bernard, N, L Cotte, Bonnet, B, C Augustin Normand, Caron, F, C Brunet-François, Philip, G, C Chapuzet, N El Alami Talbi, Chermak, A, A S Lascaux, Salmon, D, Mounoury, O, F Jeanblanc, Christine Rouzioux, M Ruquet, de Castro, N +433 morecore +1 more sourceHIV treatment simplification to elvitegravir/cobicistat/emtricitabine/tenofovir disproxil fumarate (E/C/F/TDF) plus darunavir: a pharmacokinetic study
AIDS Research and Therapy, 2017 Background As a simplification strategy for treatment-experienced HIV-infected patients who have achieved virologic suppression on a multi-drug, multi-class antiretroviral regimen, the aim of this study was to evaluate the safety, efficacy, and ...Marianne Harris, Bruce Ganase, Birgit Watson, P. Richard Harrigan, Julio S. G. Montaner, Mark W. Hull +5 moredoaj +1 more sourceDarunavir concentrations in cerebrospinal fluid and blood in HIV-1-infected individuals
, 2009 Darunavir is the most recently licensed protease inhibitor currently used in treatment-experienced HIV-infected individuals. Our objective was to determine darunavir concentrations in cerebrospinal fluid (CSF) and plasma in subjects receiving ...Price, R. W., De Meulder, M, Timmerman, P, Izadkhasthi, Arash,, Gisslén, Magnus,, Yilmaz, Aylin,, Mallon, PW +6 morecore Evaluation of the Side Effects of Antiretroviral Treatment
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2018 Introduction: The frequency of antiretroviral therapy (ART)-induced side effects varies in HIV-infected patients. In this study, we aimed to compare drug-induced side effects developing in patients receiving different ART regimens.
Materials and Methods:Sedef BAŞGÖNÜL, Serap GENÇER, Serdar ÖZER +2 moredoaj +1 more sourceHIV-1 Protease: Structural Perspectives on Drug Resistance
Viruses, 2009 Antiviral inhibitors of HIV-1 protease are a notable success of structure-based drug design and have dramatically improved AIDS therapy. Analysis of the structures and activities of drug resistant protease variants has revealed novel molecular mechanisms Irene T. Weber, Johnson Agniswamydoaj +1 more sourceDrug transporters gene expression in darunavir-treated cell lines.
, 2015 Cell lines were treated with 250 μM darunavir for 24 and 72 hours. Levels of total mRNA were measured by Real Time PCR. Relative quantitation was determined using the comparative Ct method with data normalized to three housekeeping genes (HPRT1, RPLP0 ...Georgina L. Hold (229333), Gianni Pozzi (26718), Kieron Smith (759240), Maria A. Stincarelli (759241), Francesco Iannelli (87518), Giulia De Falco (309102), Robin Shattock (114628), Charles G. Kelly (337994), Karolin Hijazi (337988), Anna M. Cuppone (759239), Julia Ekeruche-Makinde (759242) +10 morecore +1 more sourcePharmacokinetic interactions between cobicistat-boosted elvitegravir and darunavir in HIV-infected patients
, 2017 [Objectives] To evaluate if there are significant drug–drug interactions between cobicistat-boosted elvitegravir and 800 mg darunavir once daily taken simultaneously, as has been suggested previously.[Methods] The study population consisted of three ...Lopez-Cortes, Luis F, Benmarzouk-Hidalgo, Omar J, Fernández-Magdaleno, Tamara, BenMarzouk-Hidalgo, O. J., Llaves, Silvia, Espinosa, Nuria, Viciana, Pompeyo, López-Cortés, Luis F., Gutierrez-Valencia, Alicia, Gutiérrez Valencia, Alicia +9 morecore +1 more source
