Results 81 to 90 of about 18,687 (213)
Interventions for neurocognitive dysfunction [PDF]
, 2017 Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core +2 more sources
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT This case demonstrates an inverse relationship between serum carbamazepine concentration and the prothrombin time–international normalized ratio (PT‐INR) adjusted for the warfarin dose. The concomitant use of sodium valproate further contributes to an unstable PT‐INR, emphasizing the importance of careful and continuous monitoring of ...
Yuki Shirayama +5 more
wiley +1 more source
PharmacoepidemiologyBackground/Objectives: Human immunodeficiency virus (HIV) continues to be a global public health concern. Several antiretroviral drugs have been approved for the treatment, post-exposure, and pre-exposure prophylaxis of HIV. Darunavir (DRV) is a protease
Pono Pono +3 more
doaj +1 more source
Cell disposition of raltegravir and newer antiretrovirals in HIV-infected patients: high inter-individual variability in raltegravir cellular penetration [PDF]
, 2017 Objectives The site of pharmacological activity of raltegravir is intracellular. Our aim was to determine the extent of raltegravir cellular penetration and whether raltegravir total plasma concentration (Ctot) predicts cellular concentration (Ccell ...
Biollaz, Jérôme +9 more
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Testing the Substrate-Envelope Hypothesis with Designed Pairs of Compounds [PDF]
, 2013 Acquired resistance to therapeutic agents is a significant barrier to the development of clinically effective treatments for diseases in which evolution occurs on clinical time scales, frequently arising from target mutations.
Ali, Akbar +7 more
core +1 more source
Determination of Intracellular Darunavir by Liquid Chromatography Coupled with Fluorescence Detection [PDF]
, 2018 学位記番号 ...
Nagano, Daisuke +2 more
core
Improved kidney function in patients who switch their protease inhibitor from atazanavir or lopinavir to darunavir [PDF]
, 2016 OBJECTIVE: Atazanavir (ATV) and lopinavir (LPV) have been associated with kidney disease progression in HIV positive patients, with no data reported for darunavir (DRV).
Chadwick, D +9 more
core +2 more sources
PLoS ONE, 2019 BackgroundVery few data are available on treatment in HIV Late presenter population that still represents a clinical challenge.MethodsProspective, multicenter, randomized open-label, 2 arm, phase-3 trial comparing the 48-week virological response of two ...
Cristina Mussini +17 more
doaj +1 more source
Protease inhibitor monotherapy is associated with a higher level of monocyte activation, bacterial translocation and inflammation [PDF]
, 2017 Introduction Monotherapy with protease-inhibitors (MPI) may be an alternative to cART for HIV treatment. We assessed the impact of this strategy on immune activation, bacterial translocation and inflammation.
García Alcaide, Felipe +12 more
core +1 more source
Annals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.Bringing together experts in reflux diseases, including gastroenterologists, surgeons, endoscopists, laryngologists, pulmonologists, and research scientists, the inaugural Gatherings in Esophagology (GiE) was held May 30–31, 2025, in France as a new initiative of Organisation mondiale d'Etudes Spécialisées pour les maladies de l'Oesophage (OESO).
Jennifer Cable +38 more
wiley +1 more source