Results 81 to 90 of about 12,575 (207)
HIV Medicine, Volume 27, Issue 5, Page 727-739, May 2026.Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito +13 more
wiley +1 more source
BMC Infectious Diseases, 2019 Background Direct comparisons between lamivudine plus bPIs and lamivudine plus dolutegravir as maintenance strategies in virologically-suppressed HIV positive patients are lacking.
Alberto Borghetti +12 more
doaj +1 more source
Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir
Therapeutics and Clinical Risk Management, 2009 Michael Neely, Andrea KovacsUniversity of Southern California Keck School of Medicine, Department of Pediatrics, Division of infectious Diseases, Los Angeles, CA, USAAbstract: Darunavir is currently the most recently approved HIV-1 protease inhibitor. It
Michael Neely, Andrea Kovacs
doaj
Effect of particle size on release of solid dispersed particles during the "Dissolution" test
Разработка и регистрация лекарственных средствIntroduction. The use of the solid disperse systems method to increase the solubility of lipophilic active pharmaceutical ingredients is industrially applicable using different technologies, but the influence of particle size on the dissolution of these ...
S. A. Zolotov, A. V. Panov
doaj +1 more source
HIV Research & Clinical Practice, 2019 Background: The once-daily, single-tablet regimen darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg is approved for the treatment of HIV-1 infection.
Bruce Rashbaum +8 more
doaj +1 more source
Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.ABSTRACT Introduction Migrants living with HIV often face high mobility, vulnerability and limited baseline information on HIV‐1 genotype or treatment history. We aimed to assess the effectiveness and persistence of long‐acting injectable cabotegravir and rilpivirine (LAI CAB+RPV) among migrants in Spain. Methods This multicentre cohort study across 58
Jara Llenas‐García +62 more
wiley +1 more source
In vitro study of drug-drug interactions of HIV protease inhibitor darunavir on efflux ABC transporters [PDF]
, 2021 Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Dominika Bezděková Supervisor: doc. PharmDr. Lukáš Červený, Ph.D.
Bezděková, Dominika
core
European Journal of Organic Chemistry, Volume 29, Issue 9, 2 March 2026.A method for synthesizing sulfur‐substituted cyclohexenes is reportedthat leverages the η2‐coordination of a phenyl sulfone to [WTp(NO)(PMe3)] (Tp = trispyrazolylborate). Three sequential protonation and nucleophilic additions to the bound arene, followed by oxidative decomplexation, affords functionalized cyclohexenes bearing sp3‐ and sulfur‐enriched ...
Daniel J. Siela +3 more
wiley +1 more source
Drug transporters gene expression in darunavir-treated cell lines. [PDF]
, 2015 Cell lines were treated with 250 μM darunavir for 24 and 72 hours. Levels of total mRNA were measured by Real Time PCR. Relative quantitation was determined using the comparative Ct method with data normalized to three housekeeping genes (HPRT1, RPLP0 ...
Georgina L. Hold (229333) +10 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT This case demonstrates an inverse relationship between serum carbamazepine concentration and the prothrombin time–international normalized ratio (PT‐INR) adjusted for the warfarin dose. The concomitant use of sodium valproate further contributes to an unstable PT‐INR, emphasizing the importance of careful and continuous monitoring of ...
Yuki Shirayama +5 more
wiley +1 more source