Results 51 to 60 of about 18,687 (213)

Differential body composition effects of protease inhibitors recommended for initial treatment of HIV infection: A randomized clinical trial [PDF]

, 2015
This article has been accepted for publication in Clinical Infectious Diseases ©2014 The Authors .Published by Oxford University Press on Clinical Infectious Disease 60.5. DOI: 10.1093/cid/ciu898Background.
Aguilar, A., Antela, A., Arcaina, P., Arnaiz, J. A., Arnaiz, Juan A., Arribas, J. R., Asensi, V., Barrera, G., Beleta, H., Beleta, Helena, Bernardino, J. I., Bernardino, Jose I., Blanco, J. R., Cairó, M., Carton, Jose A., Cartón, J. A., Castro, J. M., Crespo, M., Curran, A., Curran, Adrià, Dalmau, D., Deulofeu, Ramon, Domingo, P., Domingo, Pere, Dronda, F., Ferrer, E., Ferrer, Elena, Garcia, D., Garcia, David, Gatell, J. M., Gatell, Jose M., Giner, L., Gonzalez-Cordon, Ana, González-Cordón, A., Gutierrez, Felix, Gutierrez, M., Gutiérrez, F., Lamas, A., Losada, E., Martinez, Esteban, Martí-Belda, P., Martínez, E., Masiá, M., Mateo, M. G., Moya, S., Murillas, J., Murillas, Javier, Negredo, E., Negredo, Eugenia, Padilla, S., Pampliega, M., Pejenaute, Andrea, Pejenaute, Andrea, Peraire, J., Peraire, Joaquim, Pich, J., Pich, Judit, Podzamczer, Daniel, Podzamczer, Daniel, Portilla, J., Portilla, Joaquin, Prieto, A., Puig, J., Pérez, I., Pérez, Ignacio, Ramos, J. R., Ramos, Nuria, Ramos, Nuria, Ribera, Esteban, Ribera, Esteban, Robledano, C., Rozas, N., Santos, I., Santos, Ignacio, Sanz, J., Saumoy, M., Vargas, M., Velli, P., Vidal, F., Viladés, C.   +79 more
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Automated Near Real‐Time QC for LC‐HRMS

Rapid Communications in Mass Spectrometry, Volume 40, Issue 10, 30 May 2026.
ABSTRACT Rationale The quality of analytical measurements is typically evaluated after completion of the entire, or possibly multiple, measurement batch(es). Automated, near real‐time quality control (QC) during LC‐HRMS acquisition can prevent reruns and sample loss by flagging issues as they occur.
Michael J. Mohr, Linus Strähle, Tobias Bader, Pia Leurle, Jan H. Christensen, Wolfram Seitz, Rudi Winzenbacher   +6 more
wiley   +1 more source

Combating HIV resistance – focus on darunavir

Therapeutics and Clinical Risk Management, 2008
Cécile L Tremblay11Department of Microbiology and Immunology, Centre Hospitalier de l’Université de Montréal, Montréal, CanadaAbstract: Darunavir is a second-generation protease inhibitor designed to ...
Cécile L Tremblay
doaj  

Virologic response to tipranavir-ritonavir or darunavir-ritonavir based regimens in antiretroviral therapy experienced HIV-1 patients: a meta-analysis and meta-regression of randomized controlled clinical trials. [PDF]

PLoS ONE, 2013
The development of tipranavir and darunavir, second generation non-peptidic HIV protease inhibitors, with marked improved resistance profiles, has opened a new perspective on the treatment of antiretroviral therapy (ART) experienced HIV patients with ...
Asres Berhan, Yifru Berhan
doaj   +1 more source

Long‐Acting PrEP for People With High Vulnerability to HIV Acquisition in Brazil: A Cost‐Effectiveness Analysis

Journal of the International AIDS Society, Volume 29, Issue 5, May 2026.
ABSTRACT Introduction In Brazil, men who have sex with men (MSM) and transgender women (TGW) remain heavily affected by HIV. Long‐acting pre‐exposure prophylaxis (LA PrEP) with injectable cabotegravir (CAB‐LA) or lenacapavir (LEN‐LA) is more effective at preventing HIV acquisition than oral PrEP.
Wanyi Chen, Paula M. Luz, Anjali Srinivasan, Beatriz Grinsztejn, Justine A. Scott, Anne M. Neilan, Valdiléa G. Veloso, Caitlin M. Dugdale, Kenneth A. Freedberg   +8 more
wiley   +1 more source

Darunavir-cobicistat versus lopinavir-ritonavir in the treatment of COVID-19 infection (DOLCI): A multicenter observational study.

PLoS ONE, 2022
BackgroundCoronavirus Disease 2019 (COVID-19) is an evolving pandemic that urged the need to investigate various antiviral therapies. This study was conducted to compare efficacy and safety outcomes of darunavir-cobicistat versus lopinavir-ritonavir in ...
Eman Zeyad I Elmekaty, Rim Alibrahim, Rania Hassanin, Sitelbanat Eltaib, Ahmed Elsayed, Fatima Rustom, Mohamed Izham Mohamed Ibrahim, Mohammed Abu Khattab, Hussam Al Soub, Muna Al Maslamani, Abdullatif Al-Khal   +10 more
doaj   +1 more source

Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik, Sean M. Hughes, Claire N. Levy, Rachel L. Creighton, Romel Mackelprang, Germán G. Gornalusse   +5 more
wiley   +1 more source

Role of darunavir in the management of HIV infection

HIV/AIDS: Research and Palliative Care, 2009
R Monica Lascar, Paul BennThe Mortimer Market Centre, Camden PCT, London WC1E 6JBAbstract: There is an ongoing need for potent antiretroviral therapies to deal with the increasing pool of treatment-experienced patients with multiple drug resistance.
R Monica Lascar, Paul Benn
doaj  

Comparative efficacy of repurposed drugs lopinavir-ritonavir and darunavir-ritonavir in hospitalised COVID-19 patients: insights from a tertiary centre cohort

Frontiers in Cellular and Infection Microbiology
BackgroundDrug repurposing has become a widely adopted strategy to minimise research time, costs, and associated risks. Combinations of protease inhibitors such as lopinavir and darunavir with ritonavir have been repurposed as treatments for COVID-19 ...
Dóra Paróczai, Dóra Paróczai, András Bikov, András Bikov, Andreea Blidaru, Emanuel Bobu, Ana Lascu, Ana Lascu, Cristian Ion Mot, Cristian Ion Mot, Stefan Mihaicuta, Stefan Mihaicuta, Stefan Frent, Stefan Frent   +13 more
doaj   +1 more source

Atazanavir-Based Therapy Is Associated with Higher Hepatitis C Viral Load in HIV Type 1-Infected Subjects with Untreated Hepatitis C [PDF]

, 2013
Comunicación cortaWe assessed the relationship between atazanavir (ATV)-based antiretroviral treatment (ART) and plasma hepatitis C virus (HCV) viral load in a population of HIV/HCV-coinfected patients.
Girón-González, José-Antonio, López Cortés, Luis Fernando, Mira, Jose A., Márquez, Manuel, Rivero-Juarez, Antonio, Santos-Gil, Ignacio De Los   +5 more
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