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A Review and Analysis of the Relationship Between Neuropsychological Measures and DAT1 in ADHD [PDF]
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2008 Contains fulltext : 69105.pdf (Publisher’s version ) (Open Access)Meta-analyses indicate that the gene coding for the dopamine transporter (DAT1 or SLC6A3) is associated with an increased risk for ADHD.
Jan Buitelaar +2 more
exaly +7 more sources
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DRD3 And DAT1 Genes in Schizophrenia: An Association Study
Journal of Psychiatric Research, 2000To investigate the role of the dopamine receptor 3 (DRD3) and transporter 1 (DAT1) genes in schizophrenia or in modulating its phenotype.a Ser9Gly polymorphism in codon 9 of the DRD3 and a VNTR polymorphism in the DAT1genes were examined in two groups of schizophrenic patients, one of excellent neuroleptic responders (N=42) and one of nonresponders (N ...
Guy A. Rouleau +2 more
exaly +3 more sources
Pharmacogenomics, 2009 Item does not contain fulltextDopamine neurotransmission has been a key player in attempts to identify genetic factors involved in alcohol dependence.
Ron Scholte +2 more
exaly +2 more sources
No Support for Association Between the Dopamine Transporter (DAT1) Gene and ADHD
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2005 Several groups have reported an association between the 10-repeat allele of a dopamine transporter (DAT1) 3UTR VNTR variant and ADHD but the finding has not been universally observed. An association between DAT1 genotype and stimulant medication response
Michael C O'Donovan +2 more
exaly +2 more sources
Novelty Seeking and a Dopamine Transporter Gene Polymorphism (DAT1)
Biological Psychiatry, 1997About 10 years ago, Cloninger defined the behavioral trait “novelty seeking” (NS) (Cloninger 1986, 1987). Two twin studies estimated the heritability of NS to be about 50% (Heath et al 1994; Stallings et al 1996). In early 1996, two papers reported significant associations between NS and a polymorphism of the type 4 dopamine receptor gene (DRD4 ...
Sullivan, Patrick F . +5 more
openaire +5 more sources
Functional Effects of the DAT1 Polymorphism on EEG Measures in ADHD
Journal of the American Academy of Child & Adolescent Psychiatry, 2003This paper examines whether dopamine transporter gene (DAT1) allele status mediates medication-related change in cognitive and neurophysiological measures among children with attention-deficiency/hyperactivity disorder (ADHD).A single 10-mg dose of methylphenidate was given in a double-blind, placebo-controlled fashion to children with ADHD who were ...
Sandra K, Loo +5 more
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Occurrence of DAT1 (VNTR) Polymorphism in Individuals with HIV Infection
Current Pharmacogenomics and Personalized Medicine, 2021Background: Antiretroviral treatment (ART) has been reported to make changes in the functioning of dopaminergic neurons by altering the expression of dopamine active transporter (DAT). ART containing efavirenz drug has been related to show the adverse reactions on the central nervous system (CNS).
HariOm Singh, Sonam Lata
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Absence of Association With DAT1 Polymorphism and Response to Methylphenidate in a Sample of Adults With ADHD [PDF]
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2006 AbstractA polymorphism in the dopamine transporter gene (DAT1) has been previously associated with ADHD and methylphenidate has been hypothesized to block the dopamine transporter. The goal of this study was to examine whether a 40‐bp variable number of tandem repeats (VNTR) of DAT1 moderate response and adverse effects associated with methylphenidate ...
Joseph Biederman +2 more
exaly +3 more sources