Results 71 to 80 of about 8,689 (241)

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing. [PDF]

PLoS ONE, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred Laucht   +9 more
doaj   +1 more source

ADHD and DAT1: Further evidence of paternal over‐transmission of risk alleles and haplotype [PDF]

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2009
AbstractWe [Hawi et al. (2005); Am J Hum Genet 77:958–965] reported paternal over‐transmission of risk alleles in some ADHD‐associated genes. This was particularly clear in the case of the DAT1 3′‐UTR VNTR. In the current investigation, we analyzed three new sample comprising of 1,248 ADHD nuclear families to examine the allelic over‐transmission of ...
Hawi, Z., Kent, L., Hill, M., Anney, R.J., Brookes, K.J., Barry, E., Franke, B., Franke, B., Banaschewski, T., Buitelaar, J.K., Ebstein, R., Miranda, A., Oades, R.D., Roeyers, H., Rothenberger, A., Sergeant, J.A., Sonuga-Barke, E.J.S., Steinhausen, H.C., Faraone, S.V., Asherson, P., Gill, M.   +20 more
openaire   +7 more sources

Minimal surfaces and eigenvalue problems

, 2013
We show that metrics that maximize the k-th Steklov eigenvalue on surfaces with boundary arise from free boundary minimal surfaces in the unit ball. We prove several properties of the volumes of these minimal submanifolds.
Fraser, Ailana, Schoen, Richard
core   +1 more source

Relationship between the Polymorphism of the AKT1 Gene and the Consumption of Cannabis in the Appearance of Psychosis

Applied Sciences, 2022
Introduction: Psychotic disorders are a mental illness that affect 3% of the world’s population. The external (cannabis) and internal vulnerability factors (polymorphisms of the AKT1 gene, the COMT gene and the DAT1 gene) acquire special relevance in the
Mónica López-Martín, Álvaro Astasio-Picado, Jesús Jurado-Palomo, María del Carmen Zabala-Baños   +3 more
doaj   +1 more source

Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). [PDF]

, 2009
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic association studies are contradictory.
Belinda Martin, Brian Lawlord, Gillian Hamilton, John Powell, Julie Williams, Michael Gill, Michael J. Owen, Michelle Lupton, Nicola Archer, Paul hollingworth, Petroula Proitsi, Simon Lovestone, Suzanne Reeves   +12 more
core   +1 more source

Neurophysiological Measures and Alcohol Use Disorder (AUD): Hypothesizing Links between Clinical Severity Index and Molecular Neurobiological Patterns [PDF]

, 2014
In 1987, Cloninger proposed a clinical description and classification of different personality traits genetically defined and independent from each other. Moreover, he elaborated a specific test the TCI to investigate these traits/states.
Attilia, Maria Luisa, Battagliese, Gemma, Berman, Marlene Oscar, Blum, Kenneth, Braverman, Eric R, Ceccanti, Mauro, Minuto, Simona Flamminii, Napolitano, Carmen, Romeo, Marina, Vitali, Mario   +9 more
core   +1 more source

Updated peer review of the pesticide risk assessment of the active substance dichlorprop‐P and variant dichlorprop‐P‐2‐ethylhexyl

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Ireland and co‐rapporteur Member State, Poland, for the pesticide active substance dichlorprop‐P and the variant dichlorprop‐P‐2‐ethylhexyl and the assessment of applications for maximum
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza, Marija Blazevic   +49 more
wiley   +1 more source

Modulation of orbitofrontal response to amphetamine by a functional variant of DAT1 and in vitro confirmation [PDF]

Molecular Psychiatry, 2010
Modulation of orbitofrontal response to amphetamine by a functional variant of DAT1 and in vitro ...
Brotons, O., O'Daly, Owen, Guindalini, C., Howard, M., Bubb, J., Barker, G., Dalton, J., Quinn, J., Murray, R. M., Breen, G., Shergill, Sukhwinder   +10 more
openaire   +4 more sources

The IMAGE project: methodological issues for the molecular genetic analysis of ADHD [PDF]

, 2006
The genetic mechanisms involved in attention deficit hyperactivity disorder (ADHD) are being studied with considerable success by several centres worldwide.
Asherson Philip, Chen Wai, Faraone Stephen V, Kuntsi Jonna, Neale Benjamin M   +4 more
core   +2 more sources

The Selective Bromodomain and Extra‐Terminal Domain (BET) Inhibitor RVX‐208 Reduces Cocaine‐Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens

Addiction Biology, Volume 31, Issue 1, January 2026.
Rats treated with the domain‐selective BET inhibitor RVX‐208 during a 2‐week forced abstinence period exhibited a reduction in cocaine‐seeking behaviour but not sucrose seeking or open field behaviour. This treatment effect was associated with proteomic changes in pathways relevant to dopaminergic and glutamatergic signalling in the nucleus accumbens ...
Tyler J. Sacko, Afshin Seyednejad, Jesse Engelhardt, Gregory C. Sartor   +3 more
wiley   +1 more source