Results 51 to 60 of about 3,265 (196)

3207 Relation between Dopamine Transporter (DAT1) polymorphism and subjective effects of alcohol among non-dependent drinkers

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Dopamine transporter (DAT1) gene variation is associated with reward-related phenotypes including alcohol response. There is also evidence for a potential moderating role for mu-opioid receptor (OPRM1) gene variation on the ...
Soundarya Soundararajan, Bethany L. Stangl, Courtney L. Vaughan, Hui Sun, Falk Lohoff, Melanie L. Schwandt, Vijay Ramchandani   +6 more
doaj   +1 more source

The effects of DAT1 genotype on fMRI activation in an emotional go/no-go task [PDF]

Brain Imaging and Behavior, 2016
Dopaminergic brain circuits participate in emotional processing and impulsivity. The dopamine transporter (DAT) modulates dopamine reuptake. A variable number tandem repeat (VNTR) in the dopamine transporter gene (DAT1) affects DAT expression. The influence of DAT1 genotype on neural activation during emotional processing and impulse inhibition has not
Brown, Brenna K., Murrell, Jill, Karne, Harish, Anand, Amit   +3 more
openaire   +2 more sources

Methylation of the DAT1 dopamine transporter gene in combat sport athletes: Associations with impulsivity and reward sensitivity

Baltic Journal of Health and Physical Activity
Epigenetic mechanisms, such as DNA methylation, modulate behavioral traits, including impulsivity and reward sensitivity. The dopamine transporter gene (DAT1) plays a key role in dopaminergic function and is associated with self-regulation, attention ...
Milena Lachowicz, Remigiusz Recław, Aleksandra SUCHANECKA, Krzysztof Chmielowiec, Elżbieta Grzywacz, Jolanta Chmielowiec, Kinga Łosińska, Anna Grzywacz   +7 more
doaj   +1 more source

Association study of promoter polymorphisms at the dopamine transporter gene in Attention Deficit Hyperactivity Disorder

BMC Psychiatry, 2009
Background Attention deficit hyperactivity disorder (ADHD) is a complex neurobehavioral disorder. The dopamine transporter gene (DAT1/SLC6A3) has been considered a good candidate for ADHD.
Huang Yu-Shu, Chen Chih-Ken, Sun Bo, Mill Jonathan, Xu Xiaohui, Wu Yu-Yu, Asherson Philip   +6 more
doaj   +1 more source

Externalizing Problem Behavior in Adolescence: Parenting Interacting With DAT1 and DRD4 Genes [PDF]

Journal of Research on Adolescence, 2016
This study extends previous gene‐by‐environment (G × E) research through design and methodological advances and examines alternative hypotheses of diathesis stress, vantage sensitivity, and differential susceptibility. In a sample of 984 adolescents and their parents, we examined whether effects of parental support, proactive, punitive, harsh punitive,
Janssens, Annelies, Van Den Noortgate, Wim, Goossens, Luc, Colpin, Hilde, Verschueren, Karine, Claes, Stephan, Van Leeuwen, Karla   +6 more
openaire   +3 more sources

Dopamine Related Genes Differentially Affect Declarative Long-Term Memory in Healthy Humans

Frontiers in Behavioral Neuroscience, 2020
In humans, monetary reward can promote behavioral performance including response times, accuracy, and subsequent recognition memory. Recent studies have shown that the dopaminergic system plays an essential role here, but the link to interindividual ...
Carla Leukel, Dirk Schümann, Raffael Kalisch, Raffael Kalisch, Raffael Kalisch, Tobias Sommer, Nico Bunzeck, Nico Bunzeck, Nico Bunzeck   +8 more
doaj   +1 more source

Upside down: dissecting impulsivity in attention-deficit hyperactivity disorder through genotype-phenotype association analyses

European Psychiatry, 2022
Introduction Better evaluation and understanding of the core symptoms have key importance both in clinical practice and the research of attention-deficit hyperactivity disorder (ADHD).
L. Balogh, A. Pulay, N. Angyal, K. Vincze, T. Kilencz, Z. Nemoda, J. Réthelyi   +6 more
doaj   +1 more source

DRD4 and DAT1 VNTR Genotyping in Children with Attention Deficit Hyperactivity Disorder [PDF]

Indian Journal of Clinical Biochemistry, 2016
The dopamine receptor-D4 and the dopamine transporter have been investigated for their role in attention deficit hyperactivity disorder (ADHD) in children. Reports of their genetic association with ADHD have shown mixed results. The aim of the study was to evaluate the association of variable number tandem repeats (VNTRs) of the DRD4 and DAT1 genes ...
Ashley, Stanley, K, Chavda, A, Subramanian, S V, Prabhu, T F, Ashavaid   +4 more
openaire   +2 more sources

The dopamine transporter gene, a spectrum of most common risky behaviors, and the legal status of the behaviors. [PDF]

PLoS ONE, 2010
This study tests the specific hypothesis that the 9R/9R genotype in the VNTR of the dopamine transporter gene (DAT1) exerts a general protective effect against a spectrum of risky behaviors in comparison to the 10R/9R and 10R/10R genotypes, drawing on ...
Guang Guo, Tianji Cai, Rui Guo, Hongyu Wang, Kathleen Mullan Harris   +4 more
doaj   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, Volume 604, Issue 11, Page 4338-4377, 1 June 2026.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source