Results 31 to 40 of about 3,746 (200)

DRD4 and DAT1 Polymorphisms Modulate Human Gamma Band Responses [PDF]

Cerebral Cortex, 2006
Gamma oscillations (30-80 Hz) have been demonstrated to be important for perceptual and cognitive processes. Animal and in vitro studies have revealed possible underlying generation mechanisms of the gamma rhythm. However, little is known about the neurochemical modulation of these oscillations during human cognition.
Tamer, Demiralp, Christoph S, Herrmann, M Emin, Erdal, Tolgay, Ergenoglu, Yasemin H, Keskin, Mehmet, Ergen, Hüseyin, Beydagi   +6 more
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Effects of interactions between variation in dopaminergic genes, traumatic life events, and anomalous self-experiences on psychosis proneness: Results from a cross-sectional study in a nonclinical sample

European Psychiatry, 2020
BackgroundThere is a growing number of studies showing interactions between genetic polymorphisms associated with dopaminergic neurotransmission and traumatic life events (TLEs) on a risk of psychotic-like experiences (PLEs).
Dorota Frydecka, Kamila Kotowicz, Łukasz Gawęda, Katarzyna Prochwicz, Joanna Kłosowska, Joanna Rymaszewska, Agnieszka Samochowiec, Jerzy Samochowiec, Piotr Podwalski, Edyta Pawlak-Adamska, Elżbieta Szmida, Andrzej Cechnicki, Błażej Misiak   +12 more
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DAT1 VNTR and ADHD

, 2021
Systematic review and meta-analysis of the association between the DAT1 VNTR polymorphism and ...
Niki H. Kamkar
core   +1 more source

The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density

BMC Genetics, 2005
Background A 40-bp variable number of tandem repeats (VNTR) polymorphism exists in the 15th exon of DAT1, the gene encoding the human dopamine transporter (DAT).
Kilts Clinton D, Owens Michael J, VanNess Sidney H   +2 more
doaj   +1 more source

Evidence of an association between 10/10 genotype of DAT1 and endophenotypes of attention deficit/hyperactivity disorder

Neurología (English Edition), 2015
Introduction: Genetic variance of attention deficit hyperactivity disorder (ADHD) is a strong determinant of this disorder. The 40 bp variable number tandem repeat (VNTR) located in the 3′ untranslated region (UTR) of DAT1 gene increases the expression ...
J.A. Agudelo, J.M. Gálvez, D.J. Fonseca, H.E. Mateus, C. Talero-Gutiérrez, A. Velez-Van-Meerbeke   +5 more
doaj   +1 more source

Association between 5HTT, DAT1, and DRD4 and bipolar disorder in youth [PDF]

Psychiatric Genetics, 2012
Bipolar disorder (BD) in youth is characterized by rapid fluctuation between high and low mood states, severe irritability, and multiple psychiatric comorbidities. Left untreated, affected youth may demonstrate compromised development in social, neurobiological, cognitive, and emotional realms (Miklowitz & Cicchetti 2006).
Cosgrove, V, Miklowitz, D, Rhee, S, Hawkey, C, Corley, R, Haberstick, B, Smolen, A   +6 more
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Evidencia de asociación entre el genotipo 10/10 de DAT1 y endofenotipos del trastorno por déficit de atención/hiperactividad

Neurología, 2015
Resumen: Introducción: La variancia genética del trastorno por déficit de atención e hiperactividad (TDAH) es determinante para el fenotipo. La repetición en tándem en número variable (VNTR) de 40 pares de bases (pb) en la región no traducida 3’ (UTR ...
J.A. Agudelo, J.M. Gálvez, D.J. Fonseca, H.E. Mateus, C. Talero-Gutiérrez, A. Velez-Van-Meerbeke   +5 more
doaj   +1 more source

Contribution of Dopamine Transporter Gene Methylation Status to Cannabis Dependency

Brain Sciences, 2020
The susceptibility to cannabis dependency results from the influence of numerous factors such as social, genetic, as well as epigenetic factors. Many studies have attempted to discover a molecular basis for this disease.
Anna Grzywacz, Wojciech Barczak, Jolanta Chmielowiec, Krzysztof Chmielowiec, Aleksandra Suchanecka, Grzegorz Trybek, Jolanta Masiak, Paweł Jagielski, Katarzyna Grocholewicz, Blazej Rubiś   +9 more
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DRD4 and DAT1 in ADHD: Functional neurobiology to pharmacogenetics

Pharmacogenomics and Personalized Medicine, 2010
Attention deficit/hyperactivity disorder (ADHD) is a common and potentially very impairing neuropsychiatric disorder of childhood. Statistical genetic studies of twins have shown ADHD to be highly heritable, with the combination of genes and gene by environment interactions accounting for around 80% of phenotypic variance. The initial molecular genetic
Turic, D., Swanson, J., Sonuga-Barke, Edmund J.S.   +2 more
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Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1) [PDF]

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2007
Abstract In this pharmacogenetic study in adults with ADHD (n = 42), a stratified analysis was performed of the association between response to methylphenidate (MPH), assessed under double‐blind conditions, and polymorphisms in the genes encoding the dopamine transporter, SLC6A3 (DAT1)
Kooij, J.S., Boonstra, A.M., Vermeulen, H.H.M., Heister, J.G.A.M., Burger, H., Buitelaar, J.K., Buitelaar, J.K., Franke, B., Franke, B.   +8 more
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