Results 31 to 40 of about 3,265 (196)

SLC6A3 (DAT1) as a Novel Candidate Biomarker Gene for Suicidal Behavior [PDF]

open access: yesGenes, 2021
It has been previously shown that the serotonin and dopamine neurotransmitter systems might influence the predisposition to suicidal behavior. This study aims to estimate the contribution of 11 polymorphisms in the genes SLC6A4 (5HTT), HTR1A, HTR2A, HTR1B, SLC6A3 (DAT1), DRD4, DRD2, COMT, and BDNF to suicidal behavior and severity of symptoms of ...
Ekaterina Rafikova   +6 more
openaire   +2 more sources

Candidate genes of the development of antipsychotic-induced parkinsonism in patients with schizophrenia

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2021
Antipsychotic-induced parkinsonism is an undesirable reaction from the extrapyramidal system that occurs against the background of taking antipsychotics (AP), more often in patients with schizophrenia.
E. E. Vaiman   +3 more
doaj   +1 more source

Determining the association between polymorphisms of the DAT1 and DRD4 genes with attention deficit hyperactivity disorder in children from Java Island

open access: yesNeurology International, 2020
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurobehavioural in the children. Genetic factor is known one of the factors which contributed in ADHD development.
Cempaka Thursina   +9 more
doaj   +1 more source

Molecular implications of repeated aggression: Th, Dat1, Snca and Bdnf gene expression in the VTA of victorious male mice. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: It is generally recognized that recurrent aggression can be the result of various psychiatric disorders. The aim of our study was to analyze the mRNA levels, in the ventral tegmental area (VTA) of the midbrain, of the genes that may possibly ...
Natalia P Bondar   +4 more
doaj   +1 more source

DRD4 and DAT1 Polymorphisms Modulate Human Gamma Band Responses [PDF]

open access: yesCerebral Cortex, 2006
Gamma oscillations (30-80 Hz) have been demonstrated to be important for perceptual and cognitive processes. Animal and in vitro studies have revealed possible underlying generation mechanisms of the gamma rhythm. However, little is known about the neurochemical modulation of these oscillations during human cognition.
Tamer, Demiralp   +6 more
openaire   +2 more sources

Effects of interactions between variation in dopaminergic genes, traumatic life events, and anomalous self-experiences on psychosis proneness: Results from a cross-sectional study in a nonclinical sample

open access: yesEuropean Psychiatry, 2020
BackgroundThere is a growing number of studies showing interactions between genetic polymorphisms associated with dopaminergic neurotransmission and traumatic life events (TLEs) on a risk of psychotic-like experiences (PLEs).
Dorota Frydecka   +12 more
doaj   +1 more source

Association between 5HTT, DAT1, and DRD4 and bipolar disorder in youth [PDF]

open access: yesPsychiatric Genetics, 2012
Bipolar disorder (BD) in youth is characterized by rapid fluctuation between high and low mood states, severe irritability, and multiple psychiatric comorbidities. Left untreated, affected youth may demonstrate compromised development in social, neurobiological, cognitive, and emotional realms (Miklowitz & Cicchetti 2006).
Cosgrove, V   +6 more
openaire   +3 more sources

DAT1 VNTR and ADHD

open access: yes, 2021
Systematic review and meta-analysis of the association between the DAT1 VNTR polymorphism and ...
Niki H. Kamkar
core   +1 more source

The role of DAT1 gene on the rapid detection of task novelty

open access: yesNeuropsychologia, 2010
In an environment with a myriad of different stimuli, the fast detection of novel and behaviorally relevant signals becomes crucial for an adaptive behavior. The detection of task-novelty has been related to striatum-prefrontal cortex (PFC) pathways involving dopaminergic (DA) neurotransmission.
Garcia-Garcia M   +3 more
openaire   +4 more sources

The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density

open access: yesBMC Genetics, 2005
Background A 40-bp variable number of tandem repeats (VNTR) polymorphism exists in the 15th exon of DAT1, the gene encoding the human dopamine transporter (DAT).
Kilts Clinton D   +2 more
doaj   +1 more source

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