Results 11 to 20 of about 3,265 (196)

Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation. [PDF]

PLoS ONE, 2012
BACKGROUND: Dopamine plays an important role in orienting, response anticipation and movement evaluation. Thus, we examined the influence of functional variants related to dopamine inactivation in the dopamine transporter (DAT1) and catechol-O ...
Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred Laucht   +9 more
doaj   +3 more sources

DAT1 and DRD4 genes involved in key dimensions of adult ADHD [PDF]

Neurological Sciences, 2015
Attention-deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder often persisting in adulthood. Genetic studies of ADHD mainly focused on the Dopamine Transporter (DAT1) and the Dopamine Receptor 4 (DRD4) genes. Nevertheless, polymorphisms of these genes explain only a small fraction of the assigned risk, suggesting ...
Hasler, Roland, Salzmann, Annick, Bolzan, Tiffany, Zimmermann, Julien, Baud, Patrick, Giannakopoulos, Panteleimon, Perroud, Nader Ali   +6 more
core   +6 more sources

Dopamine transporter (DAT1) and dopamine receptor D4 (DRD4) genotypes differentially impact on electrophysiological correlates of error processing. [PDF]

PLoS ONE, 2011
Recent studies as well as theoretical models of error processing assign fundamental importance to the brain's dopaminergic system. Research about how the electrophysiological correlates of error processing--the error-related negativity (ERN) and the ...
Stefanie C Biehl, Thomas Dresler, Andreas Reif, Peter Scheuerpflug, Jürgen Deckert, Martin J Herrmann   +5 more
doaj   +3 more sources

The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder

Frontiers in Genetics, 2014
Dysfunction in the dopaminergic and serotonergic neurotransmitter systems has been demonstrated to be important in the aetiology of Borderline personality disorder (BPD).
Peter R Joyce, John eStephenson, Martin A Kennedy, Roger T Mulder, Patrick C Mchugh   +4 more
doaj   +2 more sources

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing. [PDF]

PLoS ONE, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred Laucht   +9 more
doaj   +3 more sources

A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD [PDF]

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2008
AbstractMeta‐analyses indicate that the gene coding for the dopamine transporter (DAT1 or SLC6A3) is associated with an increased risk for ADHD. The mechanisms of this gene for ADHD are unclear. We systematically reviewed studies linking the VNTR in the 3′ UTR of the DAT1 to neurophysiological and neuropsychological measures.
Lambregts-Rommelse, N.N.J., Altink, M.E., Arias Vasquez, A., Arias Vasquez, A., Arias Vasquez, A., Buschgens, C.J.M., Fliers, E.A., Faraone, S.V., Buitelaar, J.K., Buitelaar, J.K., Sergeant, J.A., Franke, B., Franke, B., Oosterlaan, J.   +13 more
openaire   +6 more sources

DAT1 and Its Psychological Correlates in Children with Avoidant/Restrictive Food Intake Disorder: A Cross-Sectional Pilot Study

Behavioral Sciences, 2021
International research has underlined the role played by children’s and maternal psychopathological symptoms on the onset of avoidant/restrictive food intake disorder (ARFID) in early childhood.
Silvia Cimino, Eleonora Marzilli, Alessandra Babore, Carmen Trumello, Luca Cerniglia   +4 more
doaj   +2 more sources

Evidence of an association between 10/10 genotype of DAT1 and endophenotypes of attention deficit/hyperactivity disorder

Neurología (English Edition), 2015
Introduction: Genetic variance of attention deficit hyperactivity disorder (ADHD) is a strong determinant of this disorder. The 40 bp variable number tandem repeat (VNTR) located in the 3′ untranslated region (UTR) of DAT1 gene increases the expression ...
J.A. Agudelo, J.M. Gálvez, D.J. Fonseca, H.E. Mateus, C. Talero-Gutiérrez, A. Velez-Van-Meerbeke   +5 more
doaj   +2 more sources

Dopaminergic control of attentional flexibility: inhibition of return is associated with the dopamine transporter gene (DAT1)

Frontiers in Human Neuroscience, 2010
Genetic variability related to the dopamine (DA) transporter gene (DAT1) has received increasing attention as a possible modulator of human cognition. The 9-repeat allele of the DAT1 gene is presumably associated with higher striatal DA levels than the ...
Lorenza S Colzato, Jay Pratt, Bernhard Hommel   +2 more
doaj   +3 more sources

Interactive Effects of OPRM1 and DAT1 Genetic Variation on Subjective Responses to Alcohol [PDF]

Alcohol and Alcoholism, 2014
Subjective response to alcohol represents a marker of alcoholism risk. The A118G single-nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene has been associated with subjective response to alcohol. Recently, the dopamine transporter (DAT1) variable number of tandem repeat (VNTR; SLC6A3) has been found to interact with the OPRM1 A118G ...
Ray, Lara A, Bujarski, Spencer, Squeglia, Lindsay M, Ashenhurst, James R, Anton, Raymond F   +4 more
openaire   +7 more sources