Results 11 to 20 of about 3,746 (200)

Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation. [PDF]

PLoS ONE, 2012
BACKGROUND: Dopamine plays an important role in orienting, response anticipation and movement evaluation. Thus, we examined the influence of functional variants related to dopamine inactivation in the dopamine transporter (DAT1) and catechol-O ...
Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred Laucht   +9 more
doaj   +3 more sources

The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder [PDF]

Frontiers in Genetics, 2014
Dysfunction in the dopaminergic and serotonergic neurotransmitter systems has been demonstrated to be important in the aetiology of Borderline personality disorder (BPD).
Peter R Joyce, John eStephenson, Martin A Kennedy, Roger T Mulder, Patrick C Mchugh   +4 more
doaj   +2 more sources

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing. [PDF]

PLoS ONE, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred Laucht   +9 more
doaj   +3 more sources

DAT1 and DRD4 genes involved in key dimensions of adult ADHD [PDF]

Neurological Sciences, 2015
Attention-deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder often persisting in adulthood. Genetic studies of ADHD mainly focused on the Dopamine Transporter (DAT1) and the Dopamine Receptor 4 (DRD4) genes ...
Hasler, Roland, Perroud, Nader Ali, Bolzan, Tiffany, Baud, Patrick, Giannakopoulos, Panteleimon, Zimmermann, Julien, Salzmann, Annick, Zimmermann J, Perroud N, Bolzan T, Salzmann A, Baud P, Giannakopoulos P, Hasler R   +13 more
core   +5 more sources

DAT1, DRD4, and DRD5 polymorphisms are not associated with ADHD in Dutch families. [PDF]

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2004
Contains fulltext : 47606.pdf (Publisher’s version ) (Open Access)Recent meta-analyses have indicated that the dopamine transporter gene (DAT1) and the dopamine receptor genes D4 (DRD4) and D5 (DRD5) are associated with attention ...
Peter L. Pearson, Oteman, N, Jan K. Buitelaar, Schelleman, H., Steven C. Bakker, Buitelaar, J.K., Universiteit Utrecht, Pearson, P.L., Richard J. Sinke, Emma M. van der Meulen, Dep Farmaceutische wetenschappen, Nicole Oteman, Population-based studies of drug treatment: from molecule to patient outcomes, Sinke, R.J., Bakker, S.C., van der Meulen, E.M., Hedi Schelleman, Oteman, N., Meulen, E.M. van der   +18 more
core   +9 more sources

DAT1 VNTR Polymorphisms in a European and an African Population: Identification of a New Allele [PDF]

Human Biology, 2008
Polymorphism frequencies of the dopamine transporter gene (DAT1) hypervariable region have been analyzed in a sample of Italian and Ivory Coast individuals. The 3′ untranslated region (UTR) of DAT1 includes a variable number of tandem repeats (VNTR) of a
Caviglia, Gian Paolo, Cervella, Piero, Sella, Gabriella, Santovito, Alfredo, Selvaggi, Anna, Delpero, Massimiliano   +5 more
core   +5 more sources

Dopaminergic control of attentional flexibility: inhibition of return is associated with the dopamine transporter gene (DAT1) [PDF]

Frontiers in Human Neuroscience, 2010
Genetic variability related to the dopamine (DA) transporter gene (DAT1) has received increasing attention as a possible modulator of human cognition. The 9-repeat allele of the DAT1 gene is presumably associated with higher striatal DA levels than the ...
Lorenza S Colzato, Jay Pratt, Bernhard Hommel   +2 more
doaj   +2 more sources

Dopamine transporter (DAT1) VNTR polymorphism in 12 Indian populations

Neurological Sciences, 2009
The dopamine transporter (DAT1) is a membrane spanning protein that binds the neurotransmitter dopamine and performs re-uptake of dopamine from the synapse into a neuron.
Mulligan, Connie J., Nandan, Amrita, Reddy, Alla Govardhana, Sharma, Vishwas, Rao, Vadlamudi Raghavendra, Sharma, Varun Kumar, Singh, Lalji, Wasnik, Samiksha, Thangaraj, Kumarasamy, Bhaskar, L. V. K. S., Kumarasamy Thangaraj, Varun Kumar Sharma, L. V. K. S. Bhaskar, Vishwas Sharma, Samiksha Wasnik, Alla Govardhana Reddy, Lalji Singh, Connie J. Mulligan, Vadlamudi Raghavendra Rao, Amrita Nandan   +19 more
core   +3 more sources

DAT1 VNTR Allele Frequencies in the Omani Population

Human biology, 2005
To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis.
Lawatia, K, Al-Adawi, S, Al-Sharbatt, M, Simsek, M   +3 more
core   +3 more sources

Interactive Effects of OPRM1 and DAT1 Genetic Variation on Subjective Responses to Alcohol [PDF]

Alcohol and Alcoholism, 2014
AimsSubjective response to alcohol represents a marker of alcoholism risk. The A118G single-nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene has been associated with subjective response to alcohol.
Lindsay M. Squeglia, Squeglia, Lindsay M, Ashenhurst, James R, Spencer Bujarski, Ray, Lara A, Bujarski, Spencer, Raymond F. Anton, James R. Ashenhurst, Lara A. Ray, Anton, Raymond F   +9 more
core   +7 more sources