Distribution of molekular-genetic markers at sportsmen
RUDN Journal of Medicine, 2009 Results of research polymorphism carrier genes hSERT, ACE, DAT1 at sportsmen of marksmen are resulted. High frequencies of gene DAT1*10 and genotype DAT1*10/DAT1*10 at sportsmen in comparison with population, and also high frequency of heterozygotes (68 ...
N А Rudyh +4 more
doaj
DAT1 polymorphism is associated with risk taking in the Balloon Analogue Risk Task (BART).
PLoS ONE, 2012 Twin-studies suggest that a significant portion of individual differences in the propensity to take risks resides in people's genetic make-up and there is evidence that variability in dopaminergic systems relates to individual differences in risky choice.
Rui Mata +3 more
doaj +1 more source
Pharmacogenomics in children: advantages and challenges of next generation sequencing applications [PDF]
, 2013 Pharmacogenetics is considered as a prime example of how personalized medicine nowadays can be put into practice. However, genotyping to guide pharmacological treatment is relatively uncommon in the routine clinical practice. Several reasons can be found
De Paepe, Anne, Vanakker, Olivier
core +4 more sources
Mental Health Science, Volume 3, Issue 4, December 2025.ABSTRACT Attention‐deficit/hyperactivity disorder (ADHD) is associated with disordered eating habits, and individuals with eating disorders show more ADHD symptoms. Little is known about the underlying mechanism of this association. In this scoping review, we aim to provide an overview of researched mediators in adults and discuss implications for ...
Lauris Annatha Mariam Auch +3 more
wiley +1 more source
Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders. [PDF]
, 2014 Methylphenidate (MPH) reduces hyperactive-impulsive symptoms common in children with autism spectrum disorders (ASDs), however, response and tolerability varies widely.
Aman, MG +13 more
core
DNA Methylation of the Dopamine Transporter DAT1 Gene—Bliss Seekers in the Light of Epigenetics [PDF]
, 2023 Krzysztof Chmielowiec +9 more
openalex +1 more source
DAT1 and alcohol use: differential responses to life stress during adolescence [PDF]
Criminal Justice Studies, 2015 Stressful life events can impact both substance use initiation and the quantity of substances consumed by adolescents; however, the effect of stress on substance use may be contingent on other factors including social support, peers, and genotype. DAT1, a polymorphic dopamine transporter gene, is one such factor that may be responsible for differential
openaire +2 more sources
Interactive effects of dopamine transporter genotype and aging on resting-state functional networks.
PLoS ONE, 2019 Aging and dopamine modulation have both been independently shown to influence the functional connectivity of brain networks during rest. Dopamine modulation is known to decline during the course of aging.
Christian Baeuchl +5 more
doaj +1 more source
The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence
Brain and Behavior, Volume 15, Issue 10, October 2025.This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi +3 more
wiley +1 more source
Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader [PDF]
, 2019 SGK3 is a PX domain containing protein kinase activated at endosomes downstream of class 1 and 3 PI3K family members by growth factors and oncogenic mutations.
Alessi, Dario +6 more
core +2 more sources