Results 71 to 80 of about 3,837,082 (288)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Inverse Modelling to Obtain Head Movement Controller Signal [PDF]

open access: yes, 1984
Experimentally obtained dynamics of time-optimal, horizontal head rotations have previously been simulated by a sixth order, nonlinear model driven by rectangular control signals.
Hannaford, B.   +3 more
core   +1 more source

Sparse Wide-Area Control of Power Systems using Data-driven Reinforcement Learning

open access: yes, 2018
In this paper we present an online wide-area oscillation damping control (WAC) design for uncertain models of power systems using ideas from reinforcement learning.
Chakrabortty, Aranya   +2 more
core   +1 more source

Hybrid Loewner Data Driven Control

open access: yesIFAC-PapersOnLine, 2020
Abstract This article describes how the Loewner framework can be exploited to create a discrete-time control-law from input-output frequency-data of a continuous-time plant so that their hybrid interconnection matches a given continuous-time reference model up to the Nyquist frequency.
Pierre Vuillemin   +2 more
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

BLP-2LASSO for aggregate discrete choice models with rich covariates [PDF]

open access: yes, 2019
We introduce the BLP-2LASSO model, which augments the classic BLP (Berry, Levinsohn, and Pakes, 1995) random-coefficients logit model to allow for data-driven selection among a high-dimensional set of control variables using the 'double-LASSO' procedure ...
Gillen, Benjamin J.   +3 more
core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Asynchronous data retrieval from an object-oriented database [PDF]

open access: yes, 1988
We present an object-oriented semantic database model which, similar to other object-oriented systems, combines the virtues of four concepts: the functional data model, a property inheritance hierarchy, abstract data types and message-driven computation.
Bic, Lubomir, Gilbert, Jonathan P.
core  

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