Results 91 to 100 of about 34,675,582 (259)

Data-Driven Model-Free Adaptive Control Based on Error Minimized Regularized Online Sequential Extreme Learning Machine

open access: yesEnergies, 2019
Model-free adaptive control (MFAC) builds a virtual equivalent dynamic linearized model by using a dynamic linearization technique. The virtual equivalent dynamic linearized model contains some time-varying parameters, time-varying parameters usually ...
Xiaofei Zhang, Hongbin Ma
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Data-driven MPC for Real-time Control of an Open-die Forging Problem

open access: yes
International audienceModel Predictive Control (MPC) is a traditional technique widely employed to control constrained nonlinear systems. Recently, data-driven MPC has emerged as an alternative to explicit MPC strategies when sufficient data are ...
Chamoin, Ludovic   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Minimizing control cost in resource-constrained control systems: from Feedback scheduling to event-driven control [PDF]

open access: yes, 2010
This paper evaluates approaches aimed at minimizing aggregated control cost of a set of controllers that concurrently execute sharing limited computing resources. The evaluation focuses on feedback scheduling and event-driven control methods.
Manel Velasco   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Position Control of Motor Drive Systems: A Data Driven Approach

open access: yesRenewable Energy and Sustainable Development, 2015
This paper presents a new model free approach to the design of robust PID controller for the position control of electrical machines, such as induction motor, synchronous motor and DC motor faced to un-modeled dynamics. It is illustrated that knowing the
Hossein Parastvand   +2 more
doaj   +1 more source

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