Results 101 to 110 of about 2,883,845 (315)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Algebraic approach to synthesis of data-driven control design for dissipativity

open access: yesSICE Journal of Control, Measurement, and System Integration
Model-based control methods play an important role in control theory. Such controllers are designed via system identification; however, this approach is not applicable to cases where it is difficult to execute system identification owing to the large ...
Yuki Tanaka   +2 more
doaj   +1 more source

Efficient data-driven predictive control of nonlinear systems: A review and perspectives

open access: yesDigital Chemical Engineering
Model predictive control (MPC) has become a key tool for optimizing real-time operations in industrial systems and processes, particularly to enhance performance, safety, and resilience.
Xiaojie Li   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Data‐driven dual‐loop control for platooning mixed human‐driven and automated vehicles

open access: yesIET Intelligent Transport Systems
This paper considers controlling automated vehicles (AVs) to form a platoon with human‐driven vehicles (HVs) under consideration of unknown HV model parameters and propulsion time constants. The proposed design is a data‐driven dual‐loop control strategy
Jianglin Lan
doaj   +1 more source

Data-Driven Control Design for Complex Systems: Theory, Challenges, and Novel Applications

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences
This paper examines the switch from model-based to data-driven control systems, providing an overview of the challenges encountered and the potential solutions.
Chandar Kumar   +4 more
doaj   +1 more source

From Model-based to Data-driven LMI-based Controller Synthesis [PDF]

open access: yes
openThis thesis uses Linear Matrix Inequalities (LMIs) to transition from model-based to data-driven control design, while preserving guarantees with regard to stability and performance of the resulting closed-loop system.
KRASSOWIZKIY, MICHAEL
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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