Results 91 to 100 of about 35,639,582 (304)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Artificial intelligence in combustion reaction kinetics: Methods and applications
Applications in Energy and Combustion ScienceCombustion is a complex process involving fluid dynamics, heat transfer and chemical kinetics, with significant environmental impacts due to greenhouse gas and pollutant emissions.
Chenyue Tao, Chengcheng Liu, Bin Yang
doaj +1 more source
Data-Driven Interpolation of Sea Level Anomalies Using Analog Data Assimilation
Remote Sensing, 2019 From the recent developments of data-driven methods as a means to better exploit large-scale observation, simulation and reanalysis datasets for solving inverse problems, this study addresses the improvement of the reconstruction of higher-resolution Sea
Redouane Lguensat +6 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Simulation for comparing multivariate data-driven methods for industrial sensor delay estimation
, 2023 Source code and results for exactly regenerating the data and results of the simulation study reported in (to be published). Industrial sensory data is simulated and subjected to several data-driven methods for estimating temporal delays between the ...
Offermans, T (via Mendeley Data)
core +1 more source
Statistics and data science unlock the predictive power of quantitative genetics
Frontiers in Plant SciencePlant breeding is undergoing a profound transition from an empirical and phenotype-centered discipline toward a predictive, inferential, and decision-oriented science. This transformation has been driven not only by the generation of large-scale genomic,
Osval A. Montesinos-López +15 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Challenges Concerning Data-Driven Innovation [Elektronisk resurs]
, 2017 Digital transformation is highly relevant to most organisations in the business and the government sectors. One important aspect of digital transformation is the capability to exploit data in order to develop new services.
Göbel, Hannes, +2 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source