Results 71 to 80 of about 1,555,240 (261)
A Survey of Deep Learning-Based Source Image Forensics
Journal of Imaging, 2020 Image source forensics is widely considered as one of the most effective ways to verify in a blind way digital image authenticity and integrity. In the last few years, many researchers have applied data-driven approaches to this task, inspired by the ...
Pengpeng Yang +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Statistics and data science unlock the predictive power of quantitative genetics
Frontiers in Plant SciencePlant breeding is undergoing a profound transition from an empirical and phenotype-centered discipline toward a predictive, inferential, and decision-oriented science. This transformation has been driven not only by the generation of large-scale genomic,
Osval A. Montesinos-López +15 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Machine Learning Predictors of Extreme Events Occurring in Complex Dynamical Systems
Entropy, 2019 The ability to characterize and predict extreme events is a vital topic in fields ranging from finance to ocean engineering. Typically, the most-extreme events are also the most-rare, and it is this property that makes data collection and direct ...
Stephen Guth, Themistoklis P. Sapsis
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Data-Driven Methods for L2-Gain Estimation
IFAC Proceedings Volumes, 2009 In this paper we present and discuss some data-driven methods for estimation of the L2-gain of dynamical systems. Partial results on convergence and statistical properties are provided.
Barenthin, Märta +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source