Results 61 to 70 of about 4,214,964 (288)

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Humanizing Data-Driven Methods in Engineering Education Research: A Systematic Literature Review of Four Journals From 2011 to 2021

Studies in Engineering Education
Background: Quantitative methods have been frequently used in engineering education research to investigate generalizable patterns and causal relationships in phenomena of interest to the field.
Jiafu Niu, David Reeping
doaj   +1 more source

Online leakage detection system based on EWMA-enhanced Tukey method for water distribution systems

Journal of Hydroinformatics, 2023
Real-time leakage detection based on pressure and flow data has become increasingly essential for water distribution systems (WDSs). Recent data-driven leakage detection approaches have largely focused on burst detection characterised as sudden outflow ...
Xi Wan, Raziyeh Farmani, Edward Keedwell
doaj   +1 more source

Exploring galaxy evolution with generative models

, 2018
Context. Generative models open up the possibility to interrogate scientific data in a more data-driven way. Aims: We propose a method that uses generative models to explore hypotheses in astrophysics and other areas.
Schawinski, Kevin, Turp, M. Dennis, Zhang, Ce   +2 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Data–Model Fusion Methods and Applications Toward Smart Manufacturing and Digital Engineering

Engineering
As pivotal supporting technologies for smart manufacturing and digital engineering, model-based and data-driven methods have been widely applied in many industrial fields, such as product design, process monitoring, and smart maintenance. While promising,
Fei Tao, Yilin Li, Yupeng Wei, Chenyuan Zhang, Ying Zuo   +4 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Major challenges in prognostics: study on benchmarking prognostic datasets [PDF]

, 2012
Even though prognostics has been defined to be one of the most difficult tasks in Condition Based Maintenance (CBM), many studies have reported promising results in recent years.
Camci, Faith, Eker, Ömer Faruk, Jennions, Ian K.   +2 more
core  

RANS Turbulence Model Development using CFD-Driven Machine Learning

, 2020
This paper presents a novel CFD-driven machine learning framework to develop Reynolds-averaged Navier-Stokes (RANS) models. The CFD-driven training is an extension of the gene expression programming method (Weatheritt and Sandberg, 2016), but crucially ...
Akolekar, Harshal D., Michelassi, Vittorio, Sandberg, Richard D., Weatheritt, Jack, Zhao, Yaomin   +4 more
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source