Results 61 to 70 of about 1,555,240 (261)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Data‐Driven Fault Diagnosis of Drilling Tools: Methods and Applications

Engineering Reports
Effective monitoring of drilling tool condition is crucial in mechanical metal cutting to prevent tool failure, maintain machining accuracy, and ensure superior surface finish quality. Tool breakage or wear can cause catastrophic machine downtime, reduce
Chandan M. N, Himadri Majumder, Sharad Mulik, Nikhil Rangaswamy, Mukesh Kumar, Sowmyashree H. Srinivasaiah   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Direct Connection-Based Convolutional Neural Network (DC-CNN) for Fault Diagnosis of Rotor Systems

IEEE Access, 2020
Fault diagnosis of rotor systems is important to prevent unexpected failures. Recently, deep learning (DL) methods, such as a convolutional neural network (CNN), have been utilized in many research areas, including fault diagnosis.
Myungyon Kim, Joon Ha Jung, Jin Uk Ko, Hyeon Bae Kong, Jinwook Lee, Byeng Dong Youn   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Artificial intelligence in combustion reaction kinetics: Methods and applications

Applications in Energy and Combustion Science
Combustion is a complex process involving fluid dynamics, heat transfer and chemical kinetics, with significant environmental impacts due to greenhouse gas and pollutant emissions.
Chenyue Tao, Chengcheng Liu, Bin Yang
doaj   +1 more source

Data-Driven Interpolation of Sea Level Anomalies Using Analog Data Assimilation

Remote Sensing, 2019
From the recent developments of data-driven methods as a means to better exploit large-scale observation, simulation and reanalysis datasets for solving inverse problems, this study addresses the improvement of the reconstruction of higher-resolution Sea
Redouane Lguensat, Phi Huynh Viet, Miao Sun, Ge Chen, Tian Fenglin, Bertrand Chapron, Ronan Fablet   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source